業績一覧

英語論文（原著・総説）

2015年〜

Systematic analysis of plasmids of the Serratia marcescens complex using 142 closed genomes.

Nagano S. D., Taniguchi I., Ono T., Nakamura K., Gotoh Y., Hayashi T.,

Microbial Genom., 9(11), 2023.

Molecular characterization of SrSTP14, a sugar transporter from thermogenic skunk cabbage, and its possible role in developing pollen.

Koyamatsu D., Otsubo M., Ohira T., Sato MP., Suzuki-Masuko H., Shiota T., Takano KT., Ozeki M., Otsuka K., Ogura Y., Hayashi T., Watanabe M., Inaba T., Ito-Inaba Y.,

Physiol Plant., 175(4):e13957, 2023.

Phylogenic position and low genomic diversity of “Candidatus Rickettsia kotlanii” inferred by complete genome sequences of two Japanese isolates.

Gotoh Y, Takano A, Andoh M, Kasama K, Nakamura K, Ando S, Hayashi T.

Microbiol Immunol, 67(6):275-280, 2023, 

Further notice of omics profiles of fecal and oral microbiota change in irritable bowel syndrome patients with diarrhea and symptom exacerbation.

Tanaka Y, Yamashita R, Kawashima J, Mori H, Kurokawa K, Fukuda S, Gotoh Y, Nakamura K, Hayashi T, Kasahara Y, Sato Y, Fukudo S.

J Gastroenterol, 58(4):427-428, 2023, 

Genomic and phylogenetic characterization of Elizabethkingia anophelis strains: The first two cases of life-threatening infection in Japan.

Ichiki K, Ooka T, Shinkawa T, Inoue S, Hayashida M, Nakamura D, Akimoto M, Yoshimitsu M, Kawamura H, Nakamura M, Obama Y, Gotoh Y, Hayashi T, Nishi J, Ishitsuka K.

J Infect Chemother, 29(4):376-383, 2023, 

Dynamic changes in Shiga toxin (Stx) 1 transducing phage throughout the evolution of O26:H11 Stx-producing Escherichia coli.

Yano B, Taniguchi I, Gotoh Y, Hayashi T, Nakamura K.

Sci Rep, 13(1):4935, 2023, 

Global population structure, genomic diversity and carbohydrate fermentation characteristics of clonal complex 119 (CC119), an understudied Shiga toxin-producing E. coli (STEC) lineage including O165:H25 and O172:H25.

Nakamura K, Seto K, Lee K, Ooka T, Gotoh Y, Taniguchi I, Ogura Y, Mainil JG, Piérard D, Harada T, Etoh Y, Ueda S, Hamasaki M, Isobe J, Kimata K, Narimatsu H, Yatsuyanagi J, Ohnishi M, Iyoda S, Hayashi T.

Microb Genom, 9(3):mgen000959, 2023, 

Alteration of a Shiga toxin-encoding phage associated with a change in toxin production level and disease severity in Escherichia coli.

Miyata T, Taniguchi I, Nakamura K, Gotoh Y, Yoshimura D, Itoh T, Hirai S, Yokoyama E, Ohnishi M, Iyoda S, Ogura Y, Hayashi T.

Microb Genom, 9(2), 2023, 

Escherichia coli O80 in Healthy Cattle: Absence of Shigatoxigenic and Enteropathogenic E. coli O80:H2 and (Phylo) Genomics of Non-Clonal Complex 165 E. coli O80.

Ikeda R, Nakamura K, Saulmont M, Habets A, Duprez JN, Korsak N, Hayashi T, Thiry D, Mainil JG.

Microorganisms, 11(2):230, 2023, 

Insertion Sequence (IS)-Excision Enhancer (IEE)-Mediated IS Excision from the lacZ Gene Restores the Lactose Utilization Defect of Shiga Toxin-Producing Escherichia coli O121:H19 Strains and Is Responsible for Their Delayed Lactose Utilization Phenotype.

Nakamura K, Seto K, Isobe J, Taniguchi I, Gotoh Y, Hayashi T.

Appl Environ Microbiol, 88(16):e0076022, 2022, 

Draft Genome Sequences of Five Cystobasidium ongulense Strains Isolated from Areas near Syowa Station, East Antarctica.

Tsuji M, Ishihara J, Gotoh Y, Hayashi T, Takahashi H.

Microbiol Resour Announc, 11(7):e0022422, 2022, 

A Salmonella enterica Serovar Oranienburg Clone Caused a Cluster of Bacteremia Cases in Persons With No Recognizable Underlying Diseases in Japan.

Ooka T, Gotoh Y, Hatanaka S, Yoshimori M, Nishitarumizu K, Kojo K, Kosakamoto H, Sameshima K, Kuroki Y, Chibana N, Doi Y, Yoshino S, Harada T, Seto K, Ikeda T, Miyanohara H, Nakayama K, Gokuden M, Imuta N, Kawamura H, Ogura Y,Hayashi T, Nishi J.
Open Forum Infect Dis., 10(1):ofac695, 2022.

Glutamine synthetase mRNA releases sRNA from its 3’UTR to regulate carbon/nitrogen metabolic balance in Enterobacteriaceae.

Miyakoshi M, Morita T, Kobayashi A, Berger A, Takahashi H, Gotoh Y,Hayashi T, Tanaka K
Elife,11:e82411, 2022.

Omics profiles of fecal and oral microbiota change in irritable bowel syndrome patients with diarrhea and symptom exacerbation

Tanaka Y, Yamashita R, Kawashima J, Mori H, Kurokawa K, Fukuda S., Gotoh Y, Nakamura K, Hayashi T, Kasahara Y, Sato Y, Fukudo S.
J Gastroenterol, 57(10):748-760, 2022.

Single mutation makes Escherichia coli an insect mutualist.

Koga R, Moriyama M, Onodera-Tanifuji N, Ishii Y, Takai H, Mizutani M, Oguchi K, Okura R, Suzuki S, Gotoh Y, Hayashi T, Seki M, Suzuki Y, Nishide Y, Hosokawa T, Wakamoto Y, Furusawa C, Fukatsu T.
Nat Microbiol., 7(8):1141-1150, 2022.

Helicobacter cinaedi is a human-adapted lineage in the Helicobacter cinaedi/canicola/’magdeburgensis‘ complex.

Gotoh Y, Atsuta Y, Taniguchi T, Nishida R, Nakamura K, Ogura Y, Misawa N, Hayashi T.

Microb Genom, 8(5):mgen000830, 2022, 

Global population structure of the Serratia marcescens complex and identification of hospital-adapted lineages in the complex.

Ono T, Taniguchi I, Nakamura K, Nagano DS, Nishida R, Gotoh Y, Ogura Y, Sato MP, Iguchi A, Murase K, Yoshimura D, Itoh T, Shima A, Dubois D, Oswald E, Shiose A, Gotoh N, Hayashi T.

Microb Genom, 8(3):000793, 2022, 

16S rRNA gene sequence diversity in Faecalibacterium prausnitzii-complex taxa has marked impacts on quantitative analysis.

Tanno H, Maeno S, Salminen S, Gueimonde M, Endo A.

FEMS Microbiol Ecol, 98(1):fiac004, 2022, 

Year-round dynamics of amplicon sequence variant communities differ among eukaryotes, Imitervirales and prokaryotes in a coastal ecosystem.

Prodinger F, Endo H, Takano Y, Li Y, Tominaga K, Isozaki T, Blanc-Mathieu R, Gotoh Y, Hayashi T, Taniguchi E, Nagasaki K, Yoshida T, Ogata H.

FEMS Microbiol Ecol, 97(12):fiab167, 2022, 

Stepwise Evolution of a Klebsiella pneumoniae Clone within a Host Leading to Increased Multidrug Resistance.

Yoshino M, Aihara M, Gotoh Y, Akimoto M, Tatsuhara W, Kiyosuke M, Matsushima Y, Uchiumi T, Hayashi T, Kang D.

mSphere, 6(6):e0073421, 2021, 

MetaPlatanus: a metagenome assembler that combines long-range sequence links and species-specific features.

Kajitani R, Noguchi H, Gotoh Y, Ogura Y, Yoshimura D, Okuno M, Toyoda A, Kuwahara T, Hayashi T, Itoh T.

Nucleic Acids Res, 49(22):e130, 2021, 

Salicylic Acid Acts Antagonistically to Plastid Retrograde Signaling by Promoting the Accumulation of Photosynthesis-associated Proteins in Arabidopsis.

Hirosawa Y, Tada A, Matsuura T, Mori IC, Ogura Y, Hayashi T, Uehara S, Ito-Inaba Y, Inaba T.

Plant Cell Physiol, 62(11):1728-1744, 2021, 

The global population structure and evolutionary history of the acquisition of major virulence factor-encoding genetic elements in Shiga toxin-producing Escherichia coli O121:H19.

Nishida R, Nakamura K, Taniguchi I, Murase K, Ooka T, Ogura Y, Gotoh Y, Itoh T, Toyoda A, Mainil JG, Piérard D, Seto K, Harada T, Isobe J, Kimata K, Etoh Y, Hamasaki M, Narimatsu H, Yatsuyanagi J, Kameyama M, Matsumoto Y, Nagai Y, Kawase J, Yokoyama E, Ishikawa K, Shiomoto T, Lee K, Kang D, Akashi K, Ohnishi M, Iyoda S, Hayashi T.

Microb Genom, 7(12):000716, 2021, 

Uncovering the Role of Gut Microbiota in Amino Acid Metabolic Disturbances in Heart Failure Through Metagenomic Analysis.

Hayashi T, Yamashita T, Takahashi T, Tabata T, Watanabe H, Gotoh Y, Shinohara M, Kami K, Tanaka H, Matsumoto K, Hayashi T, Yamada T, Hirata K.

Front Cardiovasc Med, 8:789325, 2021, 

Diversification of Escherichia albertii H-Antigens and Development of H-Genotyping PCR.

Nakae K, Ooka T, Murakami K, Hara-Kudo Y, Imuta N, Gotoh Y, Ogura Y, Hayashi T, Okamoto Y, Nishi J.

Front Microbiol, 12:737979, 2021, 

Genome-wide association study of gastric cancer- and duodenal ulcer-derived Helicobacter pylori strains reveals discriminatory genetic variations and novel oncoprotein candidates.

Tuan VP, Yahara K, Dung HDQ, Binh TT, Tung PH, Tri TD, Thuan NPM, Khien VV, Trang TTH, Phuc BH, Tshibangu-Kabamba E, Matsumoto T, Akada J, Suzuki R, Okimoto T, Kodama M, Murakami K, Yano H, Fukuyo M, Takahashi N, Kato M, Nishiumi S, Azuma T, Ogura Y, Hayashi T, Toyoda A, Kobayashi I, Yamaoka Y.

Microb Genom, 7(11):000680, 2021, 

Comparative Genomic and Physiological Analysis against Clostridium scindens Reveals Eubacterium sp. c-25 as an Atypical Deoxycholic Acid Producer of the Human Gut Microbiota.

Song I, Gotoh Y, Ogura Y, Hayashi T, Fukiya S, Yokota A.

Microorganisms, 9(11):2254, 2021, 

Comprehensive Comparative Genomics and Phenotyping of Methylobacterium Species.

Alessa O, Ogura Y, Fujitani Y, Takami H, Hayashi T, Sahin N, Tani A.

Front Microbiol, 12:740610, 2021, 

Unexpected genomic features of high current density-producing Geobacter sulfurreducens strain YM18.

Fujikawa T, Ogura Y, Ishigami K, Kawano Y, Nagamine M, Hayashi T, Inoue K.

FEMS Microbiol Lett, 368(17):fnab119, 2021, 

Metagenomic analysis of gut microbiota reveals its role in trimethylamine metabolism in heart failure.

Emoto T, Hayashi T, Tabata T, Yamashita T, Watanabe H, Takahashi T, Gotoh Y, Kami K, Yoshida N, Saito Y, Tanaka H, Matsumoto K, Hayashi T, Yamada T, Hirata K.

Int J Cardiol, 338:138-142, 2021, 

Complete Genome Sequence of High Current-Producing Geobacter sulfurreducens Strain YM35, Isolated from River Sediment in Japan.

Fujikawa T, Ogura Y, Hayashi T, Inoue K.

Microbiol Resour Announc, 10(33):e0053921, 2021, 

“Candidatus Mesenet longicola”: Novel Endosymbionts of Brontispa longissima that Induce Cytoplasmic Incompatibility.

Takano S, Gotoh Y, Hayashi T.

Microb Ecol, 82(2):512-522, 2021, 

Development of a homogeneous time-resolved FRET (HTRF) assay for the quantification of Shiga toxin 2 produced by E. coli.

Nakamura K, Tokuda C, Arimitsu H, Etoh Y, Hamasaki M, Deguchi Y, Taniguchi I, Gotoh Y, Ogura Y, Hayashi T.

PeerJ, 9:e11871, 2021, 

Oligosaccharide Metabolism and Lipoteichoic Acid Production in Lactobacillus gasseri and Lactobacillus paragasseri.

Shiraishi T, Maeno S, Kishi S, Fujii T, Tanno H, Hirano K, Tochio T, Tanizawa Y, Arita M, Yokota S, Endo A.

Microorganisms, 9(8):1590, 2021, 

The evolution of hard tick-borne relapsing fever borreliae is correlated with vector species rather than geographical distance.

Nakao R, Kasama K, Boldbaatar B, Ogura Y, Kawabata H, Toyoda A, Hayashi T, Takano A, Maeda K.

BMC Ecol Evol, 21(1):105, 2021, 

A human respiratory tract-associated bacterium with an extremely small genome.

Fukuda K, Yamasaki K, Ogura Y, Kawanami T, Ikegami H, Noguchi S, Akata K, Katsura K, Yatera K, Mukae H, Hayashi T, Taniguchi H.

Commun Biol, 4(1):628, 2021, 

Insights into the acquisition of the pks island and production of colibactin in the Escherichia coli population.

Auvray F, Perrat A, Arimizu Y, Chagneau CV, Bossuet-Greif N, Massip C, Brugère H, Nougayrède JP, Hayashi T, Branchu P, Ogura Y, Oswald E.

Microb Genom, 7(5):000579, 2021, 

Prophages integrating into prophages: A mechanism to accumulate type III secretion effector genes and duplicate Shiga toxin-encoding prophages in Escherichia coli.

Nakamura K, Ogura Y, Gotoh Y, Hayashi T.

PLoS Pathog, 17(4):e1009073, 2021, 

A bacterial small RNA regulates the adaptation of Helicobacter pylori to the host environment.

Kinoshita-Daitoku R, Kiga K, Miyakoshi M, Otsubo R, Ogura Y, Sanada T, Bo Z, Phuoc TV, Okano T, Iida T, Yokomori R, Kuroda E, Hirukawa S, Tanaka M, Sood A, Subsomwong P, Ashida H, Binh TT, Nguyen LT, Van KV, Ho DQD, Nakai K, Suzuki T, Yamaoka Y, Hayashi T, Mimuro H.

Nat Commun, 12(1):2085, 2021, 

Niche-specific adaptation of Lactobacillus helveticus strains isolated from malt whisky and dairy fermentations.

Kido Y, Maeno S, Tanno H, Kichise Y, Shiwa Y, Endo A.

Microb Genom, 7(4):000560, 2021, 

Vitronectin binding protein, BOM1093, confers serum resistance on Borrelia miyamotoi.

Sato K, Kumagai Y, Sekizuka T, Kuroda M, Hayashi T, Takano A, Gaowa , Taylor KR, Ohnishi M, Kawabata H.

Sci Rep, 11(1):5462, 2021, 

MicroRNAs miR-4535 and miR-1915-5p in amniotic fluid as predictive biomarkers for chorioamnionitis.

Kiyoshima C, Shirasu N, Urushiyama D, Fukagawa S, Hirakawa T, Yoshikawa K, Izuchi D, Miyata K, Kurakazu M, Yotsumoto F, Hiromatsu K, Nomiyama M, Eiji O, Hirose S, Ogura Y, Hayashi T, Hata K, Nabeshima K, Yasunaga S, Miyamoto S.

Future Sci OA, 7(5):FSO686, 2021, 

Unique niche-specific adaptation of fructophilic lactic acid bacteria and proposal of three Apilactobacillus species as novel members of the group.

Maeno S, Nishimura H, Tanizawa Y, Dicks L, Arita M, Endo A.

BMC Microbiol, 21(1):41, 2021, 

Within-host evolution of a Klebsiella pneumoniae clone: selected mutations associated with the alteration of outer membrane protein expression conferred multidrug resistance.

Aihara M, Nishida R, Akimoto M, Gotoh Y, Kiyosuke M, Uchiumi T, Nishioka M, Matsushima Y, Hayashi T, Kang D.

J Antimicrob Chemother, 76(2):362-369, 2021, 

Draft Genome Sequence of Medusavirus Stheno, Isolated from the Tatakai River of Uji, Japan.

Yoshida K, Zhang R, Garcia KG, Endo H, Gotoh Y, Hayashi T, Takemura M, Ogata H.

Microbiol Resour Announc, 10(1):e01323-20, 2021, 

Genetic characterization of Shigatoxigenic and enteropathogenic Escherichia coli O80:H2 from diarrhoeic and septicaemic calves and relatedness to human Shigatoxigenic E. coli O80:H2.

Habets A, Crombé F, Nakamura K, Guérin V, De Rauw K, Piérard D, Saulmont M, Hayashi T, Mainil JG, Thiry D.

J Appl Microbiol, 130(1):258-264, 2021, 

Genomic Properties and Temporal Analysis of the Interaction of an Invasive Escherichia albertii With Epithelial Cells.

Romão FT, Martins FH, Hernandes RT, Ooka T, Santos FF, Yamamoto D, Bonfim-Melo A, Jones N, Hayashi T, Elias WP, Sperandio V, Gomes TAT.

Front Cell Infect Microbiol, 10:571088, 2020, 

12α-Hydroxylated bile acid induces hepatic steatosis with dysbiosis in rats.

Lee JY, Shimizu H, Hagio M, Fukiya S, Watanabe M, Tanaka Y, Joe GH, Iwaya H, Yoshitsugu R, Kikuchi K, Tsuji M, Baba N, Nose T, Tada K, Hanai T, Hori S, Takeuchi A, Furukawa Y, Shirouchi B, Sato M, Ooka T, Ogura Y, Hayashi T, Yokota A, Ishizuka S.

Biochim Biophys Acta Mol Cell Biol Lipids, 1865(12):158811, 2020, 

The level of antimicrobial resistance of sewage isolates is higher than that of river isolates in different Escherichia coli lineages.

Ogura Y, Ueda T, Nukazawa K, Hiroki H, Xie H, Arimizu Y, Hayashi T, Suzuki Y.

Sci Rep, 10(1):17880, 2020, 

A ubiquitous subcuticular bacterial symbiont of a coral predator, the crown-of-thorns starfish, in the Indo-Pacific.

Wada N, Yuasa H, Kajitani R, Gotoh Y, Ogura Y, Yoshimura D, Toyoda A, Tang SL, Higashimura Y, Sweatman H, Forsman Z, Bronstein O, Eyal G, Thongtham N, Itoh T, Hayashi T, Yasuda N.

Microbiome, 8(1):123, 2020, 

Genomic characterization of closely related species in the Rumoiensis clade infers ecogenomic signatures to non-marine environments.

Tanaka M, Kumakura D, Mino S, Doi H, Ogura Y, Hayashi T, Yumoto I, Cai M, Zhou YG, Gomez-Gil B, Araki T, Sawabe T.

Environ Microbiol, 22(8):3205-3217, 2020, 

Platanus_B: an accurate de novo assembler for bacterial genomes using an iterative error-removal process.

Kajitani R, Yoshimura D, Ogura Y, Gotoh Y, Hayashi T, Itoh T.

DNA Res, 27(3):dsaa014, 2020, 

16S rRNA-based amplicon analysis of changes in the bacterial population in the lesions of papillomatous digital dermatitis in dairy cattle after topical treatment with allyl isothiocyanate.

Gotoh Y, Chiba K, Sekiyama Y, Okada K, Hayashi T, Misawa N.

Microbiol Immunol, 64(6):416-423, 2020, 

Escherichia albertii Pathogenesis.

Gomes TAT, Ooka T, Hernandes RT, Yamamoto D, Hayashi T.

EcoSal Plus, 9(1), 2020, 

Mutational diversity in mutY deficient Helicobacter pylori and its effect on adaptation to the gastric environment.

Kinoshita-Daitoku R, Kiga K, Sanada T, Ogura Y, Bo Z, Iida T, Yokomori R, Kuroda E, Tanaka M, Sood A, Suzuki T, Nakai K, Hayashi T, Mimuro H.

Biochem Biophys Res Commun, 525(3):806-811, 2020, 

Complete Genome Sequence of Helicobacter pylori Strain ATCC 43504, a Type Strain That Can Infect Gerbils.

Kinoshita-Daitoku R, Ogura Y, Kiga K, Maruyama F, Kondo T, Nakagawa I, Hayashi T, Mimuro H.

Microbiol Resour Announc, 9(18):e00105-20, 2020, 

Non-pathogenic Escherichia coli acquires virulence by mutating a growth-essential LPS transporter.

Kaito C, Yoshikai H, Wakamatsu A, Miyashita A, Matsumoto Y, Fujiyuki T, Kato M, Ogura Y, Hayashi T, Isogai T, Sekimizu K.

PLoS Pathog, 16(4):e1008469, 2020, 

An Optimized Metabarcoding Method for Mimiviridae.

Prodinger F, Endo H, Gotoh Y, Li Y, Morimoto D, Omae K, Tominaga K, Blanc-Mathieu R, Takano Y, Hayashi T, Nagasaki K, Yoshida T, Ogata H.

Microorganisms, 8(4):506, 2020, 

Staphylococcus aureus Virulence Affected by an Alternative Nisin A Resistance Mechanism.

Kawada-Matsuo M, Watanabe A, Arii K, Oogai Y, Noguchi K, Miyawaki S, Hayashi T, Komatsuzawa H.

Appl Environ Microbiol, 86(8):e02923-19, 2020, 

Hypoosmotic stress induces flagellar biosynthesis and swimming motility in Escherichia albertii.

Ikeda T, Shinagawa T, Ito T, Ohno Y, Kubo A, Nishi J, Gotoh Y, Ogura Y, Ooka T, Hayashi T.

Commun Biol, 3(1):87, 2020, 

Group A Streptococcus establishes pharynx infection by degrading the deoxyribonucleic acid of neutrophil extracellular traps.

Tanaka M, Kinoshita-Daitoku R, Kiga K, Sanada T, Zhu B, Okano T, Aikawa C, Iida T, Ogura Y, Hayashi T, Okubo K, Kurosawa M, Hirahashi J, Suzuki T, Nakagawa I, Nangaku M, Mimuro H.

Sci Rep, 10(1):3251, 2020, 

Epidemiological Aspects of Escherichia albertii Outbreaks in Japan and Genetic Characteristics of the Causative Pathogen.

Masuda K, Ooka T, Akita H, Hiratsuka T, Takao S, Fukada M, Inoue K, Honda M, Toda J, Sugitani W, Narimatsu H, Ishioka T, Hirai S, Sekizuka T, Kuroda M, Morita Y, Hayashi T, Kimura H, Oishi K, Ohnishi M, Fujimoto S, Murakami K.

Foodborne Pathog Dis, 17(2):144-150, 2020, 

Escherichia coli O8:H8 Carrying a Novel Variant of the Heat-Labile Enterotoxin LT2 Gene Caused Outbreaks of Diarrhea.

Ishimaru K, Sasaki M, Narimatsu H, Arimizu Y, Gotoh Y, Nakamura K, Hayashi T, Ogura Y.

Open Forum Infect Dis, 7(1):ofaa021, 2020, 

Differential dynamics and impacts of prophages and plasmids on the pangenome and virulence factor repertoires of Shiga toxin-producing Escherichia coli O145:H28.

Nakamura K, Murase K, Sato MP, Toyoda A, Itoh T, Mainil JG, Piérard D, Yoshino S, Kimata K, Isobe J, Seto K, Etoh Y, Narimatsu H, Saito S, Yatsuyanagi J, Lee K, Iyoda S, Ohnishi M, Ooka T, Gotoh Y, Ogura Y, Hayashi T.

Microb Genom, 6(1):e000323, 2020, 

Genomic Features of Rickettsia heilongjiangensis Revealed by Intraspecies Comparison and Detailed Comparison With Rickettsia japonica.

Kasama K, Fujita H, Yamamoto S, Ooka T, Gotoh Y, Ogura Y, Ando S, Hayashi T.

Front Microbiol, 10:2787, 2019, 

Genotypic diversity of Streptococcus suis and the S. suis-like bacterium Streptococcus ruminantium in ruminants.

Okura M, Maruyama F, Ota A, Tanaka T, Matoba Y, Osawa A, Sadaat SM, Osaki M, Toyoda A, Ogura Y, Hayashi T, Takamatsu D.

Vet Res, 50(1):94, 2019, 

O-antigen biosynthesis gene clusters of Escherichia albertii: their diversity and similarity to Escherichia coli gene clusters and the development of an O-genotyping method.

Ooka T, Seto K, Ogura Y, Nakamura K, Iguchi A, Gotoh Y, Honda M, Etoh Y, Ikeda T, Sugitani W, Konno T, Kawano K, Imuta N, Yoshiie K, Hara-Kudo Y, Murakami K, Hayashi T, Nishi J.

Microb Genom, 5(11):e000314, 2019, 

Comparison of the sequencing bias of currently available library preparation kits for Illumina sequencing of bacterial genomes and metagenomes.

Sato MP, Ogura Y, Nakamura K, Nishida R, Gotoh Y, Hayashi M, Hisatsune J, Sugai M, Takehiko I, Hayashi T.

DNA Res, 26(5):391-398, 2019, 

The Earth Is Small for “Leviathans”: Long Distance Dispersal of Giant Viruses across Aquatic Environments.

Li Y, Endo H, Gotoh Y, Watai H, Ogawa N, Blanc-Mathieu R, Yoshida T, Ogata H.

Microbes Environ, 34(3):334-339, 2019, 

Large-scale genome analysis of bovine commensal Escherichia coli reveals that bovine-adapted E. coli lineages are serving as evolutionary sources of the emergence of human intestinal pathogenic strains.

Arimizu Y, Kirino Y, Sato MP, Uno K, Sato T, Gotoh Y, Auvray F, Brugere H, Oswald E, Mainil JG, Anklam KS, Döpfer D, Yoshino S, Ooka T, Tanizawa Y, Nakamura Y, Iguchi A, Morita-Ishihara T, Ohnishi M, Akashi K, Hayashi T, Ogura Y.

Genome Res, 29(9):1495-1505, 2019, 

Arsenate and microbial dynamics in different phosphorus regimes of the subtropical Pacific Ocean.

Hashihama F, Suwa S, Kanda J, Ehama M, Sakuraba R, Kinouchi S, Sato M, Yamaguchi T, Saito H, Ogura Y, Hayashi T, Mori H, Kurokawa K, Suzuki S, Hamasaki K.

Progress in Oceanography, 176:102115, 2019, 

Metagenomic and metabolomic analyses reveal distinct stage-specific phenotypes of the gut microbiota in colorectal cancer.

Yachida S, Mizutani S, Shiroma H, Shiba S, Nakajima T, Sakamoto T, Watanabe H, Masuda K, Nishimoto Y, Kubo M, Hosoda F, Rokutan H, Matsumoto M, Takamaru H, Yamada M, Matsuda T, Iwasaki M, Yamaji T, Yachida T, Soga T, Kurokawa K, Toyoda A, Ogura Y, Hayashi T, Hatakeyama M, Nakagama H, Saito Y, Fukuda S, Shibata T, Yamada T.

Nat Med, 25(6):968-976, 2019, 

Alternative Oxidase Capacity of Mitochondria in Microsporophylls May Function in Cycad Thermogenesis.

Ito-Inaba Y, Sato M, Sato MP, Kurayama Y, Yamamoto H, Ohata M, Ogura Y, Hayashi T, Toyooka K, Inaba T.

Plant Physiol, 180(2):743-756, 2019, 

Evaluation of SNP calling methods for closely related bacterial isolates and a novel high-accuracy pipeline: BactSNP.

Yoshimura D, Kajitani R, Gotoh Y, Katahira K, Okuno M, Ogura Y, Hayashi T, Itoh T.

Microb Genom, 5(5):e000261, 2019, 

Local structural changes of the influenza A virus ribonucleoprotein complex by single mutations in the specific residues involved in efficient genome packaging.

Takizawa N, Ogura Y, Fujita Y, Noda T, Shigematsu H, Hayashi T, Kurokawa K.

Virology, 531:126-140, 2019, 

Genome Sequencing Verifies Relapsed Infection of Helicobacter cinaedi.

Sawada O, Gotoh Y, Taniguchi T, Furukawa S, Yoshimura D, Sasaki S, Shida H, Kusunoki Y, Yamamura T, Furuya K, Itoh T, Horita T, Hayashi T, Misawa N.

Open Forum Infect Dis, 6(5):ofz200, 2019, 

BspR/BtrA, an Anti-σ Factor, Regulates the Ability of Bordetella bronchiseptica To Cause Cough in Rats.

Nakamura K, Shinoda N, Hiramatsu Y, Ohnishi S, Kamitani S, Ogura Y, Hayashi T, Horiguchi Y.

mSphere, 4(2):e00093-19, 2019, 

Draft Genome Sequence of Mycolicibacterium sp. Strain NCC-Tsukiji, Isolated from Blood Culture of a Patient with Malignant Lymphoma.

Fukano H, Yoshida M, Shouji M, Hatta S, Maruyama D, Izutsu K, Shiotsuka M, Ogura Y, Hayashi T, Hasegawa N, Iwata S, Hoshino Y.

Microbiol Resour Announc, 8(14):e01575-18, 2019, 

Phenotypic characterization and virulence-related properties of Escherichia albertii strains isolated from children with diarrhea in Brazil.

Lima MP, Yamamoto D, Santos ACdM, Ooka T, Hernandes RT, Vieira MAM, Santos FF, Silva RM, Hayashi T, Gomes TAT.

Pathog Dis, 77(2):ftz014, 2019, 

A highly efficient method for concentrating DNA from river water by combined coagulation and foam separation.

Suzuki Y, Imafuku Y, Nishiyama M, Teranishi K, Jikumaru A, Nukazawa K, Ogura Y.

Separation Science and Technology, 54(18):3128-3134, 2019, 

Multi-step genomic dissection of a suspected intra-hospital Helicobacter cinaedi outbreak.

Gotoh Y, Taniguchi T, Yoshimura D, Katsura K, Saeki Y, Hirabara Y, Fukuda M, Takajo I, Tomida J, Kawamura Y, Ogura Y, Itoh T, Misawa N, Okayama A, Hayashi T.

Microb Genom, 4(12):e000236, 2018, 

Genomic Characterization of β-Glucuronidase-Positive Escherichia coli O157:H7 Producing Stx2a.

Ogura Y, Seto K, Morimoto Y, Nakamura K, Sato MP, Gotoh Y, Itoh T, Toyoda A, Ohnishi M, Hayashi T.

Emerg Infect Dis, 24(12):2219-2227, 2018, 

Effects of bacterial pollution caused by a strong typhoon event and the restoration of a recreational beach: Transitions of fecal bacterial counts and bacterial flora in beach sand.

Suzuki Y, Teranishi K, Matsuwaki T, Nukazawa K, Ogura Y.

Sci Total Environ, 640-641:52-61, 2018, 

Amylibacter kogurei sp. nov., a novel marine alphaproteobacterium isolated from the coastal sea surface microlayer of a marine inlet.

Wong SK, Yoshizawa S, Nakajima Y, Cuadra MJ, Nogi Y, Nakamura K, Takami H, Ogura Y, Hayashi T, Chiura HX, Hamasaki K.

Int J Syst Evol Microbiol, 68(9):2872-2877, 2018, 

Mycobacterium shigaense sp. nov., a slow-growing, scotochromogenic species, is a member of the Mycobacterium simiae complex.

Fukano H, Yoshida M, Kazumi Y, Fujiwara N, Katayama K, Ogura Y, Hayashi T, Miyamoto Y, Fujimoto N, Hongsheng W, Mizumoto C, Koizumi Y, Maeda H, Hiranuma O, Mitarai S, Ishii N, Hoshino Y.

Int J Syst Evol Microbiol, 68(8):2437-2442, 2018, 

Tracing Genomic Divergence of Vibrio Bacteria in the Harveyi Clade.

Ke HM, Liu D, Ogura Y, Hayashi T, Urbanczyk H, Tsai IJ.

J Bacteriol, 200(15):e00001-18, 2018, 

Complete Genome Sequence of Mycobacterium shigaense.

Yoshida M, Fukano H, Ogura Y, Kazumi Y, Mitarai S, Hayashi T, Hoshino Y.

Genome Announc, 6(25):e00552-18, 2018, 

Availability of Nanopore sequences in the genome taxonomy for Vibrionaceae systematics: Rumoiensis clade species as a test case.

Tanaka M, Mino S, Ogura Y, Hayashi T, Sawabe T.

PeerJ, 6:e5018, 2018, 

Draft Genome Sequence of Saccharospirillum sp. Strain MSK14-1, Isolated from Surface Seawater Collected at Aburatsubo Inlet in Japan.

Hasegawa M, Nakajima Y, Wong SK, Nakamura K, Ogura Y, Hayashi T, Kogure K, Yoshizawa S.

Genome Announc, 6(22):e00469-18, 2018, 

Naturally occurring a loss of a giant plasmid from Mycobacterium ulcerans subsp. shinshuense makes it non-pathogenic.

Nakanaga K, Ogura Y, Toyoda A, Yoshida M, Fukano H, Fujiwara N, Miyamoto Y, Nakata N, Kazumi Y, Maeda S, Ooka T, Goto M, Tanigawa K, Mitarai S, Suzuki K, Ishii N, Ato M, Hayashi T, Hoshino Y.

Sci Rep, 8(1):8218, 2018, 

Complete Genome Sequence of Geobacter sulfurreducens Strain YM18, Isolated from River Sediment in Japan.

Inoue K, Ogura Y, Kawano Y, Hayashi T.

Genome Announc, 6(19):e00352-18, 2018, 

Solar-panel and parasol strategies shape the proteorhodopsin distribution pattern in marine Flavobacteriia.

Kumagai Y, Yoshizawa S, Nakajima Y, Watanabe M, Fukunaga T, Ogura Y, Hayashi T, Oshima K, Hattori M, Ikeuchi M, Kogure K, DeLong EF, Iwasaki W.

ISME J, 12(5):1329-1343, 2018, 

Small RNA repertoires and their intraspecies variation in Aggregatibacter actinomycetemcomitans.

Oogai Y, Gotoh Y, Ogura Y, Kawada-Matsuo M, Hayashi T, Komatsuzawa H.

DNA Res, 25(2):207-215, 2018, 

Presence of a Haloarchaeal Halorhodopsin-Like Cl⁻ Pump in Marine Bacteria.

Nakajima Y, Tsukamoto T, Kumagai Y, Ogura Y, Hayashi T, Song J, Kikukawa T, Demura M, Kogure K, Sudo Y, Yoshizawa S.

Microbes Environ, 33(1):89-97, 2018, 

Comparison of the microbial community structure between inflamed and non-inflamed sites in patients with ulcerative colitis.

Hirano A, Umeno J, Okamoto Y, Shibata H, Ogura Y, Moriyama T, Torisu T, Fujioka S, Fuyuno Y, Kawarabayasi Y, Matsumoto T, Kitazono T, Esaki M.

J Gastroenterol Hepatol, 33(9):1590-1597, 2018, 

R-Spondin1 expands Paneth cells and prevents dysbiosis induced by graft-versus-host disease.

Hayase E, Hashimoto D, Nakamura K, Noizat C, Ogasawara R, Takahashi S, Ohigashi H, Yokoi Y, Sugimoto R, Matsuoka S, Ara T, Yokoyama E, Yamakawa T, Ebata K, Kondo T, Hiramine R, Aizawa T, Ogura Y, Hayashi T, Mori H, Kurokawa K, Tomizuka K, Ayabe T, Teshima T.

J Exp Med, 214(12):3507-3518, 2017, 

Complete Chromosome Sequence of a Mycolactone-Producing Mycobacterium, Mycobacterium pseudoshottsii.

Yoshida M, Miyamoto Y, Ogura Y, Hayashi T, Hoshino Y.

Genome Announc, 5(48):e01363-17, 2017, 

Complete and Draft Genome Sequences of Eight Oceanic Pseudomonas aeruginosa Strains.

Kumagai Y, Yoshizawa S, Nakamura K, Ogura Y, Hayashi T, Kogure K.

Genome Announc, 5(44):e01255-17, 2017, 

Isolation of six novel 7-oxo- or urso-type secondary bile acid-producing bacteria from rat cecal contents.

Tawthep S, Fukiya S, Lee JY, Hagio M, Ogura Y, Hayashi T, Yokota A.

J Biosci Bioeng, 124(5):514-522, 2017, 

Population structure of Escherichia coli O26 : H11 with recent and repeated stx2 acquisition in multiple lineages.

Ogura Y, Gotoh Y, Itoh T, Sato MP, Seto K, Yoshino S, Isobe J, Etoh Y, Kurogi M, Kimata K, Maeda E, Piérard D, Kusumoto M, Akiba M, Tominaga K, Kirino Y, Kato Y, Shirahige K, Ooka T, Ishijima N, Lee K, Iyoda S, Mainil JG, Hayashi T.

Microb Genom, 3(11):e000141, 2017, 

Draft Genome Sequence of Rubricoccus marinus SG-29^T, a Marine Bacterium within the Family Rhodothermaceae, Which Contains Two Different Rhodopsin Genes.

Nakajima Y, Yoshizawa S, Park S, Kumagai Y, Wong SK, Ogura Y, Hayashi T, Kogure K.

Genome Announc, 5(38):e00990-17, 2017, 

Genomic Characteristics of Bifidobacterium thermacidophilum Pig Isolates and Wild Boar Isolates Reveal the Unique Presence of a Putative Mobile Genetic Element with tetW for Pig Farm Isolates.

Tsuchida S, Maruyama F, Ogura Y, Toyoda A, Hayashi T, Okuma M, Ushida K.

Front Microbiol, 8:1540, 2017, 

Algibacter aquaticus sp. nov., a slightly alkaliphilic marine Flavobacterium isolated from coastal surface water.

Wong SK, Park S, Lee JS, Lee KC, Ogura Y, Hayashi T, Chiura HX, Yoshizawa S, Hamasaki K.

Int J Syst Evol Microbiol, 67(7):2199-2204, 2017, 

Thaumasiovibrio occultus gen. nov. sp. nov. and Thaumasiovibrio subtropicus sp. nov. within the family Vibrionaceae, isolated from coral reef seawater off Ishigaki Island, Japan.

Amin AKMR, Tanaka M, Al-Saari N, Feng G, Mino S, Ogura Y, Hayashi T, Meirelles PM, Thompson FL, Gomez-Gil B, Sawabe T, Sawabe T.

Syst Appl Microbiol, 40(5):290-296, 2017, 

Vibrio aphrogenes sp. nov., in the Rumoiensis clade isolated from a seaweed.

Tanaka M, Endo S, Kotake F, Al-Saari N, Amin AKMR, Feng G, Mino S, Doi H, Ogura Y, Hayashi T, Suda W, Hattori M, Yumoto I, Sawabe T, Sawabe T, Araki T.

PLoS One, 12(6):e0180053, 2017, 

Clonal Lineages of Erysipelothrix rhusiopathiae Responsible for Acute Swine Erysipelas in Japan Identified by Using Genome-Wide Single-Nucleotide Polymorphism Analysis.

Ogawa Y, Shiraiwa K, Ogura Y, Ooka T, Nishikawa S, Eguchi M, Hayashi T, Shimoji Y.

Appl Environ Microbiol, 83(11):e00130-17, 2017, 

A Geographically Widespread Outbreak Investigation and Development of a Rapid Screening Method Using Whole Genome Sequences of Enterohemorrhagic Escherichia coli O121.

Lee K, Morita-Ishihara T, Iyoda S, Ogura Y, Hayashi T, Sekizuka T, Kuroda M, Ohnishi M, EHEC Working Group in Japan.

Front Microbiol, 8:701, 2017, 

Identification of Shiga toxin-producing (STEC) and enteropathogenic (EPEC) Escherichia coli in diarrhoeic calves and comparative genomics of O5 bovine and human STEC.

Fakih I, Thiry D, Duprez JN, Saulmont M, Iguchi A, Piérard D, Jouant L, Daube G, Ogura Y, Hayashi T, Taminiau B, Mainil JG.

Vet Microbiol, 202:16-22, 2017, 

Draft Genome Sequences of Tersicoccus phoenicis DSM 30849^T, Isolated from a Cleanroom for Spacecraft Assembly, and Tersicoccus sp. Strain Bi-70, Isolated from a Freshwater Lake.

Nakajima Y, Yoshizawa S, Nakamura K, Ogura Y, Hayashi T, Kogure K.

Genome Announc, 5(13):e00079-17, 2017, 

Identification of a New Virulent Clade in Enterohemorrhagic Escherichia coli O26:H11/H- Sequence Type 29.

Ishijima N, Lee K, Kuwahara T, Nakayama-Imaohji H, Yoneda S, Iguchi A, Ogura Y, Hayashi T, Ohnishi M, Iyoda S.

Sci Rep, 7:43136, 2017, 

Extraintestinal infection of Helicobacter cinaedi induced by oral administration to Balb/c mice.

Taniguchi T, Saeki Y, Okayama A, Hayashi T, Misawa N.

Microbiol Immunol, 61(2):57-63, 2017, 

Extremely Low Genomic Diversity of Rickettsia japonica Distributed in Japan.

Akter A, Ooka T, Gotoh Y, Yamamoto S, Fujita H, Terasoma F, Kida K, Taira M, Nakadouzono F, Gokuden M, Hirano M, Miyashiro M, Inari K, Shimazu Y, Tabara K, Toyoda A, Yoshimura D, Itoh T, Kitano T, Sato MP, Katsura K, Mondal SI, Ogura Y, Ando S, Hayashi T.

Genome Biol Evol, 9(1):124-133, 2017, 

Complete Genome Sequence of Streptococcus sp. Strain NPS 308.

Kondo Y, Ogura Y, Sato K, Imamura K, Hoshino T, Nishiguchi M, Hasuwa T, Moriuchi H, Hayashi T, Fujiwara T.

Genome Announc, 4(6):e01349-16, 2016, 

Genes essential for the morphogenesis of the Shiga toxin 2-transducing phage from Escherichia coli O157:H7.

Mondal SI, Islam MR, Sawaguchi A, Asadulghani M, Ooka T, Gotoh Y, Kasahara Y, Ogura Y, Hayashi T.

Sci Rep, 6:39036, 2016, 

Mitochondrial Genome Sequences of Four Strains of the Bloom-Forming Raphidophyte Heterosigma akashiwo.

Ogura Y, Nakayama N, Hayashi T, Ueki S.

Genome Announc, 4(6):e01288-16, 2016, 

Draft Genome Sequences of Two Fabibacter sp. Strains Isolated from Coastal Surface Water of Aburatsubo Inlet, Japan.

Kaneko R, Wong SK, Ogura Y, Hayashi T, Yoshizawa S, Hamasaki K.

Genome Announc, 4(6):e01360-16, 2016, 

Non-exponential growth of Mycobacterium leprae Thai-53 strain cultured in vitro.

Amako K, Iida K, Saito M, Ogura Y, Hayashi T, Yoshida S.

Microbiol Immunol, 60(12):817-823, 2016, 

Complete Genome Sequence of a Phycodnavirus, Heterosigma akashiwo Virus Strain 53.

Ogura Y, Hayashi T, Ueki S.

Genome Announc, 4(6):e01279-16, 2016, 

Complete Genome Sequence of Klebsiella oxytoca Strain JKo3.

Iwase T, Ogura Y, Hayashi T, Mizunoe Y.

Genome Announc, 4(6):e01221-16, 2016, 

Complete Genome Sequence of Mycobacterium ulcerans subsp. shinshuense.

Yoshida M, Nakanaga K, Ogura Y, Toyoda A, Ooka T, Kazumi Y, Mitarai S, Ishii N, Hayashi T, Hoshino Y.

Genome Announc, 4(5):e01050-16, 2016, 

Phylogenetic Analysis of Enteroaggregative Escherichia coli (EAEC) Isolates from Japan Reveals Emergence of CTX-M-14-Producing EAEC O25:H4 Clones Related to Sequence Type 131.

Imuta N, Ooka T, Seto K, Kawahara R, Koriyama T, Kojyo T, Iguchi A, Tokuda K, Kawamura H, Yoshiie K, Ogura Y, Hayashi T, Nishi J.

J Clin Microbiol, 54(8):2128-34, 2016, 

Genomic evidence that Vibrio inhibens is a heterotypic synonym of Vibrio jasicida.

Urbanczyk Y, Ogura Y, Hayashi T, Urbanczyk H.

Int J Syst Evol Microbiol, 66(8):3214-3218, 2016, 

Draft Genome Sequence of Lewinella sp. Strain 4G2 Isolated from the Coastal Sea Surface Microlayer.

Wong SK, Yoshizawa S, Nakajima Y, Ogura Y, Hayashi T, Hamasaki K.

Genome Announc, 4(4):e00754-16, 2016, 

Colistin-Resistant mcr-1-Positive Pathogenic Escherichia coli in Swine, Japan, 2007-2014.

Kusumoto M, Ogura Y, Gotoh Y, Iwata T, Hayashi T, Akiba M.

Emerg Infect Dis, 22(7):1315-7, 2016, 

Domestication and cereal feeding developed domestic pig-type intestinal microbiota in animals of suidae.

Ushida K, Tsuchida S, Ogura Y, Toyoda A, Maruyama F.

Anim Sci J, 87(6):835-41, 2016, 

Draft Genome Sequences of Five Rapidly Growing Mycobacterium Species, M. thermoresistibile, M. fortuitum subsp. acetamidolyticum, M. canariasense, M. brisbanense, and M. novocastrense.

Katahira K, Ogura Y, Gotoh Y, Hayashi T.

Genome Announc, 4(3):e00322-16, 2016, 

Six Novel O Genotypes from Shiga Toxin-Producing Escherichia coli.

Iguchi A, Iyoda S, Seto K, Nishii H, Ohnishi M, Mekata H, Ogura Y, Hayashi T.

Front Microbiol, 7:765, 2016, 

The pathogenic potential of Helicobacter cinaedi isolated from non-human sources: adherence, invasion and translocation ability in polarized intestinal epithelial Caco-2 cells in vitro.

Taniguchi T, Yamazaki W, Saeki Y, Takajo I, Okayama A, Hayashi T, Misawa N.

J Vet Med Sci, 78(4):627-32, 2016, 

Genetic relatedness and virulence properties of enteropathogenic Escherichia coli strains of serotype O119:H6 expressing localized adherence or localized and aggregative adherence-like patterns on HeLa cells.

Garcia BG, Ooka T, Gotoh Y, Vieira MAM, Yamamoto D, Ogura Y, Girão DM, Sampaio SCF, Melo AB, Irino K, Hayashi T, Gomes TAT.

Int J Med Microbiol, 306(3):152-64, 2016, 

Complete Genome Sequence of Klebsiella pneumoniae YH43.

Iwase T, Ogura Y, Hayashi T, Mizunoe Y.

Genome Announc, 4(2):e00242-16, 2016, 

Emergence of a Multidrug-Resistant Shiga Toxin-Producing Enterotoxigenic Escherichia coli Lineage in Diseased Swine in Japan.

Kusumoto M, Hikoda Y, Fujii Y, Murata M, Miyoshi H, Ogura Y, Gotoh Y, Iwata T, Hayashi T, Akiba M.

J Clin Microbiol, 54(4):1074-81, 2016, 

HlyF Produced by Extraintestinal Pathogenic Escherichia coli Is a Virulence Factor That Regulates Outer Membrane Vesicle Biogenesis.

Murase K, Martin P, Porcheron G, Houle S, Helloin E, Pénary M, Nougayrède JP, Dozois CM, Hayashi T, Oswald E.

J Infect Dis, 213(5):856-65, 2016, 

The genomic basis of parasitism in the Strongyloides clade of nematodes.

Hunt VL, Tsai IJ, Coghlan A, Reid AJ, Holroyd N, Foth BJ, Tracey A, Cotton JA, Stanley EJ, Beasley H, Bennett HM, Brooks K, Harsha B, Kajitani R, Kulkarni A, Harbecke D, Nagayasu E, Nichol S, Ogura Y, Quail MA, Randle N, Xia D, Brattig NW, Soblik H, Ribeiro DM, Sanchez-Flores A, Hayashi T, Itoh T, Denver DR, Grant W, Stoltzfus JD, Lok JB, Murayama H, Wastling J, Streit A, Kikuchi T, Viney M, Berriman M.

Nat Genet, 48(3):299-307, 2016, 

Draft Genome Sequences of Sarcina ventriculi Strains Isolated from Wild Japanese Macaques in Yakushima Island.

Ushida K, Tsuchida S, Ogura Y, Hayashi T, Sawada A, Hanya G.

Genome Announc, 4(1):e01694-15, 2016, 

The complete genome sequencing of Prevotella intermedia strain OMA14 and a subsequent fine-scale, intra-species genomic comparison reveal an unusual amplification of conjugative and mobile transposons and identify a novel Prevotella-lineage-specific repeat.

Naito M, Ogura Y, Itoh T, Shoji M, Okamoto M, Hayashi T, Nakayama K.

DNA Res, 23(1):11-9, 2016, 

A New Screen for Tuberculosis Drug Candidates Utilizing a Luciferase-Expressing Recombinant Mycobacterium bovis Bacillus Calmette-Guéren.

Ozeki Y, Igarashi M, Doe M, Tamaru A, Kinoshita N, Ogura Y, Iwamoto T, Sawa R, Umekita M, Enany S, Nishiuchi Y, Osada-Oka M, Hayashi T, Niki M, Tateishi Y, Hatano M, Matsumoto S.

PLoS One, 10(11):e0141658, 2015, 

The Shiga toxin 2 production level in enterohemorrhagic Escherichia coli O157:H7 is correlated with the subtypes of toxin-encoding phage.

Ogura Y, Mondal SI, Islam MR, Mako T, Arisawa K, Katsura K, Ooka T, Gotoh Y, Murase K, Ohnishi M, Hayashi T.

Sci Rep, 5:16663, 2015, 

Defining the Genome Features of Escherichia albertii, an Emerging Enteropathogen Closely Related to Escherichia coli.

Ooka T, Ogura Y, Katsura K, Seto K, Kobayashi H, Kawano K, Tokuoka E, Furukawa M, Harada S, Yoshino S, Seto J, Ikeda T, Yamaguchi K, Murase K, Gotoh Y, Imuta N, Nishi J, Gomes TA, Beutin L, Hayashi T.

Genome Biol Evol, 7(12):3170-9, 2015, 

Draft Genome Sequence of Lactobacillus gorillae Strain KZ01^T, Isolated from a Western Lowland Gorilla.

Tsuchida S, Nezuo M, Tsukahara M, Ogura Y, Hayashi T, Ushida K.

Genome Announc, 3(5):e01196-15, 2015, 

Description of a novel marine bacterium, Vibrio hyugaensis sp. nov., based on genomic and phenotypic characterization.

Urbanczyk Y, Ogura Y, Hayashi T, Urbanczyk H.

Syst Appl Microbiol, 38(5):300-4, 2015, 

Draft Genome Sequence of the Archiascomycetous Yeast Saitoella complicata.

Yamauchi K, Kondo S, Hamamoto M, Takahashi Y, Ogura Y, Hayashi T, Nishida H.

Genome Announc, 3(3):e00220-15, 2015, 

Persistence and Epidemic Propagation of a Pseudomonas aeruginosa Sequence Type 235 Clone Harboring an IS26 Composite Transposon Carrying the bla_IMP-1 Integron in Hiroshima, Japan, 2005 to 2012.

Shimizu W, Kayama S, Kouda S, Ogura Y, Kobayashi K, Shigemoto N, Shimada N, Yano R, Hisatsune J, Kato F, Hayashi T, Sueda T, Ohge H, Sugai M.

Antimicrob Agents Chemother, 59(5):2678-87, 2015, 

Ecophysiology of Thioploca ingrica as revealed by the complete genome sequence supplemented with proteomic evidence.

Kojima H, Ogura Y, Yamamoto N, Togashi T, Mori H, Watanabe T, Nemoto F, Kurokawa K, Hayashi T, Fukui M.

ISME J, 9(5):1166-76, 2015, 

Complete Genome Sequence of Methylobacterium aquaticum Strain 22A, Isolated from Racomitrium japonicum Moss.

Tani A, Ogura Y, Hayashi T, Kimbara K.

Genome Announc, 3(2):e00266-15, 2015, 

Polymorphisms Influencing Expression of Dermonecrotic Toxin in Bordetella bronchiseptica.

Okada K, Abe H, Ike F, Ogura Y, Hayashi T, Fukui-Miyazaki A, Nakamura K, Shinzawa N, Horiguchi Y.

PLoS One, 10(2):e0116604, 2015, 

A complete view of the genetic diversity of the Escherichia coli O-antigen biosynthesis gene cluster.

Iguchi A, Iyoda S, Kikuchi T, Ogura Y, Katsura K, Ohnishi M, Hayashi T, Thomson NR.

DNA Res, 22(1):101-7, 2015, 

2010年〜2014年

Contrasting inter- and intraspecies recombination patterns in the “Harveyi clade” vibrio collected over large spatial and temporal scales.

Urbanczyk H., Ogura Y., Hayashi T.

Genome Biol. Evol., 7: 71–80, 2014. 

Assessment of helminth biodiversity in wild rats using 18S rDNA based metagenomics.

Tanaka R., Hino A., Tsai I.J., Emilio P-R, Yoshida A., Ogura Y., Hayashi T., Maruyama H. Kikuchi T.

PLoS One, 23;9(10):e110769, 2014. 

Finding a human telomere DNA-RNA Hybrid G-quadruplex formed by human telomeric 6-mer RNA and 16-mer DNA using click chemistry: A protective structure for telomere end.

Xu Y., Suzuki Y., Hayashi T., Komiyama M.

Bioorg. Med. Chem., 22: 4419-4421, 2014. 

Genome evolution and plasticity of Serratia marcescens, an important multidrug-resistant nosocomial pathogen.

Iguchi A., Nagaya Y., Pradel E., Ooka T., Ogura Y., Katsura K., Kurokawa K., Oshima K., Hattori M., Parkhill J., Sebaihia M., Coulthurst S., Gotoh N., Thomson N.R., Ewbank J.J., Hayashi T.

Genome Biol. Evol., 6: 2096-2110, 2014. 

Efficient de novo assembly of highly heterozygous genomes from whole-genome shotgun short reads.

Kajitani R., Toshimoto K., Noguchi H., Toyoda A., Ogura Y., Okuno M., Yabana M., Harada M., Nagayasu E., Maruyama H., Kohara Y., Fujiyama A., Hayashi T., Itoh T.

Genome Res., 24: 1384-1395, 2014. 

Complete genome sequence of Bordetella bronchiseptica S798, an isolate from a pig with atrophic rhinitis.

Okada K., Ogura Y., Hayashi T., Abe A., Kuwae A., Horiguchi Y., Abe H.

Genome Announc., 2(3):e00436-14, 2014. 

Functional characterization of flavobacteria rhodopsins reveals a unique class of light-driven chloride pump in bacteria.

Yoshizawa S., Kumagai Y., Kim H., Ogura Y., Hayashi T., Iwasaki W., DeLong E.F., Kogure K.

Proc. Natl. Acad. Sci. USA, 111:6732-6737, 2014. 

Various pAQU plasmids possibly contribute to disseminate tetracycline resistance gene tet(M) among marine bacterial community.

Nonaka L., Maruyama F., Onishi Y., Kobayashi T., Ogura Y., Hayashi T., Suzuki S., Masuda M.

Front. Microbiol., 12 May 2014, doi: 10.3389/fmicb.2014.00152. 

Molecular characterization of cytolethal distending toxin gene-positive Escherichia coli from healthy cattle and swine in Nara, Japan.

Hinenoya A., Shima K., Asakura M., Nishimura K., Tsukamoto T., Ooka T., Hayashi T., Ramamurthy T., Faruque S., Yamasaki S.

BMC Microbiology, 14: 97, 2014. 

Phylogenetic clades 6 and 8 of enterohemorrhagic Escherichia coli O157:H7 with particular stx subtypes are more frequently found in isolates from hemolytic uremic syndrome patients than from asymptomatic carriers.

Iyoda S., Manning S.D., Seto K., Kimata K., Isobe J., Etoh Y., Ichihara S., Migita Y., Ogata K., Honda M., Kubota T., Kawano K., Matsumoto K., Kudaka J., Asai N., Yabata J., Tominaga K., Terajima J., Morita-Ishihara T., Izumiya H., Ogura Y., Saitoh T., Iguchi A., Kobayashi H., Hara-Kudo Y., Ohnishi M., EHEC Working Group in Japan

Open Forum Infect. Dis., 12;1(2):ofu061, 2014. 

Complete genome sequence of Pseudomonas sp. strain TKP, isolated from a γ-hexachlorocyclohexane- degrading mixed culture.

Ohtsubo Y., Kishida K., Sato T., Tabata M., Kawasumi T., Ogura Y., Hayashi T., Tsuda M., Nagata Y.

Genome Announc., 2(1). pii: e01241-13, 2014. 

A novel small regulatory RNA enhances cell motility in enterohemorrhagic Escherichia coli.

Sudo N., Soma A., Muto A., Iyoda S., Suh M., Kurihara N., Abe H., Tobe T., Ogura Y., Hayashi T., Kurokawa K., Ohnishi M., Sekine Y.

J. Gen. Appl. Microbiol., 60: 44-50, 2014.　

Lineage-specific distribution of insertion sequence excision enhancer in enterotoxigenic Escherichia coli isolated from swine.

Kusumoto M., Fukamizu D., Ogura Y., Yoshida E., Yamamoto F., Iwata T., Ooka T., Akiba M., Hayashi T.

Appl. Environ. Microbiol., 80: 1394-1402, 2014. 

Complete genome sequence of Pseudomonas aeruginosa MTB-1, isolated from a microbial community enriched by the technical formulation of hexachlorocyclohexane.

Ohtsubo Y., Sato T., Kishida K., Tabata M., Ogura Y., Hayashi T., Tsuda M., Nagata Y.

Genome Announc., 23;2(1), 2014. 

Draft genome sequence of Clostridium botulinum type B strain Osaka05, isolated from an infant patient with botulism in Japan.

Sakaguchi Y., Hosomi K., Uchiyama J., Ogura Y., Umeda K., Sakaguchi M., Kohda T., Mukamoto M., Misawa N., Matsuzaki S., Hayashi T., Kozaki S.

Genome Announc., 23;2(1), 2014. 

Updating the Vibrio clades defined by multilocus sequence phylogeny: proposal of eight new clades, and the description of Vibrio tritonius sp. nov.

Sawabe T., Ogura Y., Matsumura Y., Feng G., Amin AKM R., Mino S., Nakagawa S., Sawabe T., Kumar R., Fukui Y., Satomi M., Matsushima R., Thompson F. L., Gomez Gil B., Christen R., Maruyama F., Kurokawa K., Hayashi T.

Front. Microbiol., 27;4:414, 2013. 

Diversification of two lineages of symbiotic Photobacterium.

Urbanczyk H., Urbanczyk Y., Hayashi T., Ogura Y.

PLoS One, 2013 Dec 13;8(12):e82917. 

Rapid identification and subtyping of Helicobacter cinaedi strains by intact-cell mass spectrometry profiling with the use of matrix-assisted laser desorption ionization-time of flight mass spectrometry.

Taniguchi T., Sekiya A., Higa M., Saeki Y., Umeki K., Okayama A., Hayashi T., Misawa N.

J. Clin. Microbiollin. Microbiol. 52: 95-102, 2014. 

Direct light-up of cAMP derivatives in living cells by click reactions.

Ito K., Liu H., Komiyama K., Hayashi T., Xu Y.

Molecules, 18 :12909-12915, 2013. 

Whole-Genome Sequence of the Potentially Hypertransmissible Multidrug-Resistant Mycobacterium tuberculosis Beijing Strain OM-V02_005.

Tateishi Y., Tamaru A., Ogura Y., Niki M., Wada T., Yamamoto T., Hirata K., Hayashi T., Matsumoto S.

Genome Announc., 1(4). pii: e00608-13, 2013. 

Comparative evaluation of agar dilution and broth microdilution methods for antibiotic susceptibility testing of Helicobacter cinaedi.

Tomida J., Oumi A., Okamoto T., Morita Y., Okayama A., Misawa N., Hayashi T., Akaike T., Kawamura Y.

Microbiol. Immunol., 57:353-358, 2013. 

Involvement of the novel two-component NsrRS and LcrRS systems in distinct resistance pathways against nisin A and nukacin ISK-1 in Streptococcus mutans.

Kawada-Matsuo M., Oogai Y., Zendo T., Nagao J., Shibata Y., Yamashita Y., Ogura Y., Hayashi T., Sonomoto K., Komatsuzawa H.

Appl. Environ. Microbiol., 79: 4751-4755, 2013. 

Taxonomic revision of Harveyi clade bacteria (family Vibrionaceae) based on analysis of whole genome sequences.

Urbanczyk H., Ogura Y., Hayashi T.

Int. J. Syst. Evol. Microbiol., 63: 2742-2751, 2013. 

PhoB regulates the survival of Bacteroides fragilis in peritoneal abscesses.

Wakimoto S., Nakayama-Imaohji H., Ichimura M., Morita H., Hirakawa H., Hayashi T., Yasutomo K., Kuwahara T.

PLoS One, 8(1): e53829, 2013. 

Complete genome sequence of a Propionibacterium acnes isolate from a sarcoidosis patient.

Minegishi K., Aikawa C., Furukawa A., Watanabe T., Nakano T., Ogura Y., Ohtsubo Y., Kurokawa K., Hayashi T., Maruyama F., Nakagawa I., Eishi Y.

Genome Announc., 1(1): e00016-12, 2013. 

Human gastroenteritis outbreak associated with Escherichia albertii, Japan.

Ooka T., Tokuoka E., Fukuhara M., Nagamura T., Ogura Y., Aisawa K., Harada S., Hayashi T.

Emerg. Infect. Dis., 19: 144-146, 2013. 

Transcriptomic analysis of four developmental stages of Strongyloides venezuelensis.

Nagayasu E., Ogura Y., Itoh T., Yoshida A., Chakraborty G., Hayashi T., Maruyama H.

Parasitol. Int., 62: 57-65, 2013. 

Oligonucleotide models of telomeric DNA and RNA form a hybrid G-quadruplex structure as a potential component of telomeres.

Xu Y., Ishizuka T., Yang J., Ito K., Katada H., Komiyama M., Hayashi T.

J. Biol. Chemiol. Chem., 287: 41787-41796, 2012. 

Whole-genome sequence of the hypervirulent clinical strain Mycobacterium intracellulare M.i.198.

Tateishi Y., Kitada S., Miki K., Maekura R., Ogura Y., Ozeki Y., Nishiuchi Y., Niki M., Hayashi T., Hirata K., Kobayashi K., Matsumoto S.

J. Bacteriol., 194: 6336, 2012. 

Complete genome sequence of Bacillus cereus NC7401, which produces high levels of the emetic toxin cereulide.

Takeno A., Okamoto A., Tori K., Oshima K., Hirakawa H., Toh H., Agata N., Yamada K., Ogasawara N., Hayashi T., Shimizu T., Kuhara S., Hattori M., Ohta M.

J. Bacteriol., 194: 4767-4768, 2012. 

Is bile acid a determinant of the gut microbiota on a high-fat diet?

Yokota A., Fukiya S., Ooka T., Ogura Y., Hayashi T., Ishizuka S.

Gut Microbes, 3: 455-459, 2012. 

Complete genome sequence of Helicobacter cinaedi strain PAGU611, isolated in a case of human bacteremia.

Goto T., Ogura Y., Hirakawa H., Tomida J., Morita Y., Akaike T., Hayashi T., Kawamura Y.

J. Bacteriol., 194: 3744-3745, 2012. 

Detection of diverse aquatic microbes in blood and organs of drowning victims: First metagenomic approach using high-throughput 454-pyrosequencing.

Kakizaki E., Ogura Y., Kozawa S., Nishida S., Uchiyama T., Hayashi T., Yukawa N.

Forensic Sci. Int., 220: 135-146, 2012. 

A sensitive and simple plaque formation method for the Stx2 phage of Escherichia coli O157:H7, which does not form plaques in the standard plating procedure.

Islam Md.R., Ogura Y., Asdulghani Md., Ooka T., Murase K., Gotoh Y., Hayashi T.

Plasmid, 67: 227-235, 2012. 

Haemolysin E- and enterohaemolysin-derived haemolytic activity of O55/O157 strains and other Escherichia coli lineages.

Murase K., Ooka T., Iguchi A., Ogura Y., Nakayama K., Asadulghani Md., Islam Md.R., Hiyoshi H., Kodama T., Beutin L., Hayashi T.

Microbiology, 158: 746-758, 2012. 

Clinical significance of Escherichia albertii.

Ooka T., Seto K., Kawano K., Kobayashi H., Etoh Y., Ichihara S., Kaneko A., Isobe J., Yamaguchi K., Horikawa K., Gomes TA., Linden A., Bardiau M., Mainil JG., Beutin L., Ogura Y., Hayashi T.

Emerg. Infect. Dis., 18: 488-492, 2012. 

Culture-negative brain abscess with Streptococcus intermedius infection with diagnosis established by direct nucleotide sequence analysis of the 16S ribosomal RNA gene.

Saito N., Hida A., Koide Y., Ooka T., Ichikawa Y., Shimizu J., Mukasa A., Nakatomi H., Hatakeyama S., Hayashi T., Tsuji S.

Intern. Med., 51: 211-216, 2012. 

Typing of O26 enterohaemorrhagic and enteropathogenic Escherichia coli isolated from humans and cattle with IS621 multiplex PCR-based fingerprinting.

Mainil JG., Bardiau M., Ooka T., Ogura Y., Murase K., Etoh Y., Ichihara S., Horikawa K., Buvens G., Piérard D., Itoh T., Hayashi T.

J. Appl. Microbiol., 111: 773-786, 2011. 

Bile acid is a host factor that regulates the composition of the cecal microbiota in rats.

Islam KB., Fukiya S., Hagio M., Fujii N., Ishizuka S., Ooka T., Ogura Y., Hayashi T., Yokota A.

Gastroenterology, 141: 1773-1781, 2011. 

Wide distribution of O157-antigen biosynthesis gene clusters in Escherichia coli.

Iguchi A., Shirai H., Seto K., Ooka T., Ogura Y., Hayashi T., Osawa K., Osawa R.

PLoS One, 6(8): e23250, 2011. 

The lifestyle of the segmented filamentous bacterium: a non-culturable gut-associated immunostimulating microbe inferred by whole-genome sequencing.

Kuwahara T., Ogura Y., Oshima K., Kurokawa K., Ooka T., Hirakawa H., Itoh T., Nakayama-Imaohji H., Ichimura M., Itoh K., Ishifune C., Maekawa Y., Yasutomo K., Hattori M., Hayashi T.

DNA Res., 18: 291-303, 2011. 

Characterization of the Porphyromonas gingivalis conjugative transposon CTnPg1: determination of the integration site and the genes essential for conjugal transfer.

Naito M., Sato K., Shoji M., Yukitake H., Ogura Y., Hayashi T., Nakayama K.

Microbiology, 157: 2022-2032. 2011. 

The genome of Erysipelothrix rhusiopathiae, the causative agent of swine erysipelas, reveals new insights into the evolution of Firmicutes and the organism’s intracellular adaptations.

Ogawa Y., Ooka T., Shi F., Ogura Y., Nakayama K., Hayashi T., Shimoji Y.

J. Bacteriol., 193: 2959-2971, 2011. 

Genome sequence of Photobacterium mandapamensis strain svers.1.1, the bioluminescent symbiont of the cardinal fish Siphamia versicolor.

Urbanczyk H., Ogura Y., Hendry TA., Gould AL., Kiwaki N., Atkinson JT., Hayashi T., Dunlap PV.

J. Bacteriolacteriol., 193: 3144-3145, 2011. 

Enterotypes of the human gut microbiome.

Arumugam M., Raes J., Pelletier E., Paslier DL.,Yamada T., Mende DR., Fernandes GR., Tap J., Bruls T., Batto JM. , Bertalan M., Borruel N., Casellas F., Fernandez L., Gautier L., Hansen T., Hattori M., Hayashi T., Kleerebezem M., Kurokawa K., Leclerc M., Levenez F., Manichanh C., Nielsen HB., Nielsen T., Pons N., Poulain J., Qin J., Sicheritz-Ponten T., Tims S., Torrents D., Ugarte E., Zoetendal EG., Wang J., Guarner F., Pedersen O., Vos de WM., Brunak S., Doré J., MetaHIT Consortium, Weissenbach J., Ehrlich SD., Bork P.

Nature, 473: 174-180, 2011. 

Insertion sequence-excision enhancer removes transposable elements from bacterial genomes and induces various genomic deletions.

Kusumoto M., Ooka T., Nishiya Y., Ogura Y., Saito T., Sekine Y., Iwata T., Akiba M., Hayashi T.

Nat. Commun., 2:152, 2011. 

NleC, a type III secretion protease, compromises NF-κB activation by targeting p65/RelA.

Yen H., Ooka T., Iguchi A., Hayashi T., Sugimoto N., Tobe T.

PLoS Pathog., 6(12): e1001 231, 2010. 

New system for multilocus variable-number tandem-repeat analysis of the enterohemorrhagic Escherichia coli strains belonging to three major serogroups: O157, O26, and O111.

Izumiya H., Pei Y., Terajima J., Ohnishi M., Hayashi T., Iyoda S., Watanabe H.

Microbiol. Immunol., 54: 569-577, 2010. 

Genome comparison and phylogenetic analysis of Orientia tsutsugamushi strains.

Nakayama K., Kurokawa K., M. Fukuhara, Urakami H., Yamamoto S., Yamazaki K., Ogura Y., Ooka T., Hayashi T.

DNA Res., 17: 281-291, 2010. 

Efficient electrotransformation of Bacteroides fragilis.

Ichimura M., Nakayama-Imaohji H., Wakimoto S., Morita H., Hayashi T., Kuwahara T.

Appl. Environ. Microbiol., 76: 3325-3332, 2010. 

Identification of candidate pathogens of papillomatous digital dermatitis in dairy cattle from quantitative 16S rRNA clonal analysis.

Yano T., Moe K. K., Yamazaki K., Ooka T., Hayashi T., Misawa N.

Vet. Microbiol., 134: 352-362, 2010. 

Complete genome sequence of the wild-type commensal Escherichia coli strain SE15, belonging to phylogenetic group B2.

Toh H., Oshima K., Toyoda A., Ogura Y., Ooka T., Sasamoto H., Park S.H., Iyoda S., Kurokawa K., Morita H., Itoh K., Taylor T.D., Hayashi T., Hattori M.

J. Bacteriol., 192: 1165-1166, 2010. 

2005年〜2009年

Comparative genomics reveal the mechanism of the parallel evolution of O157 and non-O157 enterohemorrhagic Escherichia coli.

Ogura Y., Ooka T., Iguchi A., Toh H., Asadulghani Md., Oshima K., Kodama T., Abe H., Nakayama K., Kurokawa K., Tobe T., Hattori M., Hayashi T.

Proc. Natl. Acad. Sci. USA, 106: 17939-17944, 2009. 

Enterohaemorrhagic Escherichia coli serogroup O111 inhibits NF-(kappa)B-dependent innate responses in a manner independent of a type III secreted OspG orthologue.

Nobe R., Nougayrède J.P., Taieb F., Bardiau M., Cassart D., Navarro-Garcia F., Mainil J.G., Hayashi T., Oswald E.

Microbiology, 155: 3214-3225, 2009. 

Identification of the site-specific DNA invertase responsible for the phase variation of SusC/SusD family outer membrane proteins in Bacteroides fragilis.

Nakayama-Imaohji H., Hirakawa H. Ichimura M., Wakimoto S., Kuhara S., Hayashi T., Kuwahara T.

J. Bacteriol., 191: 6003-6011, 2009. 

Development of a multiplex PCR-based rapid typing method for enterohemorrhagic Escherichia coli O157 strains.

Ooka T., Terajima J., Kusumoto M., Iguchi A., Kurokawa K., Ogura Y., Asadulghani M., Nakayama K., Murase K., Ohnishi M., Iyoda S., Watanabe H., Hayashi T.

J. Clin. Microbiol., 47: 2888-2894, 2009. 

Pulsed-field gel electrophoresis profile changes resulting from spontaneous chromosomal deletions in enterohemorrhagic Escherichia coli O157:H7 during passage in cattle.

Yoshii N., Ogura Y., Hayashi T., Ajiro T., Sameshima T., Nakazawa M., Kusumoto M., Iwata T., Akiba M.

Appl. Environ. Microbiol., 75: 5719-5726, 2009. 

Inference of the impact of insertion sequence (IS) elements on bacterial genome diversification through analysis of small-size structural polymorphisms in Escherichia coli O157 genomes.

Ooka T., Ogura Y., Asadulghani Md., Ohnishi M., Nakayama K., Terajima J., Watanabe H., Hayashi T.

Genome Res., 19: 1809-1816, 2009. 

A precise reconstruction of the emergence and constrained radiations of Escherichia coli O157 portrayed by backbone concatenomic analysis.

Leopold S.R., Magrini V., Holt N.J., Shaikh N., Mardis E.R., Cagno J., Ogura Y., Iguchi A., Hayashi T., Mellmann A., Karch H., Besser T.E., Sawyer S.A., Whittam T.S., Tarr P.I.

Proc. Natl. Acad. Sci. USA, 106: 8713-8718, 2009. 

The defective prophage pool of Escherichia coli O157: prophage-prophage interactions potentiate horizontal transfer of virulence determinants.

Asadulghani Md., Ogura Y., Ooka T., Itoh T., Sawaguchi A., Iguchi A., Nakayama K., Hayashi T.

PLoS Pathog., 5(5) e1000408, 2009. 

Molecular analysis of an extrachromosomal element containing the C2 toxin gene discovered in Clostridium botulinum type C.

Sakaguchi Y., Hayashi T., Yamamoto Y., Nakayama K., Zhang K., Ma S., Arimitsu H., Oguma K.

J. Bacteriol., 191: 3282-3291, 2009. 

Genetic heterogeneity among strains of Treponema phagedenis-like spirochetes isolated from dairy cattle with papillomatous digital dermatitis in Japan.

Yano T., Yamagami R., Misumi K., Kubota C., Moe K.K., Hayashi T., Yoshitani K., Ohtake O., Misawa N.

J. Clin. Microbiol., 47: 727-733, 2009. 

Enterohemorrhagic Escherichia coli effector EspL2 induces actin microfilament aggregation through annexin 2 activation.

Miyahara A., Nakanishi N., Ooka T., Hayashi T., Sugimoto N., Tobe T.

Cell Microbiol., 11: 337-350, 2009. 

Regulation of virulence by butyrate sensing in enterohaemorrhagic Escherichia coli.

Nakanishi N., Tashiro K., Kuhara S., Hayashi T., Sugimoto N., Tobe T.

Microbiology, 155: 521-530, 2009. 

Simple broad-spectrum protocol using labiase for bacterial cell lysis to prepare genomic DNA for pulsed-field gel electrophoresis analysis.

Oana K., Kawakami Y., Hayashi T., Ohnishi M.

Microbiol. Immunol., 53: 45-48, 2009. 

Complete genome sequence and comparative genome analysis of enteropathogenic Escherichia coli O127:H6 strain E2348/69.

Iguchi A., Thomson N.R., Ogura Y., Saunders D., Ooka T., Henderson I.R., Harris D., Asadulghani, Kurokawa K., Dean P., Kenny B., Quail M.A., Thurston S., Dougan G., Hayashi T., Parkhill J., Frankel G.

J. Bacteriol., 191: 347-354, 2009. 

Complete genome sequence and comparative analysis of the wild-type commensal Escherichia coli strain SE11 isolated from a healthy adult.

Oshima K., Toh H., Ogura Y., Sasamoto H., Morita H., Park S.-H., Ooka T., Iyoda S., Taylor T.D., Hayashi T., Itoh K., Hattori M.

DNA Res., 15: 375-386, 2008. 

Systematic identification and sequence analysis of the genomic islands of the enteropathogenic Escherichia coli strain B171-8 by the combined use of whole-genome PCR scanning and fosmid mapping.

Ogura Y., Abe H., Katsura K., Kurokawa K., Asadulghani, Iguchi A., Ooka T., Nakayama K., Yamashita A., Hattori M., Tobe T., Hayashi T.

J. Bacteriol., 190: 6948-6960, 2008. 

Determination of the genome sequence of Porphyromonas gingivalis strain ATCC 33277 and genomic comparison with strain W83 revealed extensive genome rearrangements in P. gingivalis.

Naito M., Hirakawa H., Yamashita A., Ohara N., Shoji M., Yukitake H., Nakayama K., Toh H., Yoshimura F., Kuhara S., Hattori M., Hayashi T., Nakayama K.

DNA Res., 15: 215-225, 2008. 

The whole-genome sequencing of the obligate intracellular bacterium Orientia tsutsugamushi revealed massive gene amplification during reductive genome evolution.

Nakayama K., Yamashita A., Kurokawa K., Morimoto T., Ogawa M., Fukuhara M., Urakami H., Ohnishi M., Uchiyama I., Ogura Y., Ooka T., Oshima K., Tamura A., Hattori M., Hayashi T.

DNA Res., 15: 185-199, 2008. 

Comparative genomic analysis using microarray demonstrates a strong correlation between the presence of the 80-kilobase pathogenicity island and pathogenicity in Kanagawa phenomenon-positive Vibrio parahaemolyticus strains.

Izutsu K., Kurokawa K., Tashiro K., Kuhara S., Hayashi T., Honda T., Iida T.

Infect. Immun., 76: 1016-1023, 2008. 

High-level fluoroquinolone resistance in ophthalmic clinical isolates belonging to the species Corynebacterium macginleyi.

Eguchi H., Kuwahara T., Miyamoto T., Nakayama-Imaohji H., Ichimura M., Hayashi T., Shiota H.

J. Clin. Microbiol., 46: 527-532, 2008. 

Genomic comparison of the O-antigen biosynthesis gene clusters of Escherichia coli O55 strains belonging to three distinct lineages.

Iguchi A., Ooka T., Ogura Y., Asadulghani, Nakayama K., Frankel G. and Hayashi T.

Microbiology, 154: 559-570, 2008. 

Global regulation by horizontally transferred regulators establishes the pathogenicity of Escherichia coli.

Abe H., Miyahara A., Oshima T., Tashiro K., Ogura Y., Kuhara S., Ogasawara N., Hayashi T., Tobe T.

DNA Res., 15: 25-38, 2008. 

Distribution, functional expression, and genetic organization of Cif, a phage-encoded type III-secreted effector from enteropathogenic and enterohemorrhagic Escherichia coli.

Loukiadis E., Nobe R., Herold S., Tramuta C., Ogura Y., Ooka T., Morabito S., Kerouredan M., Brugere H., Schmidt H., Hayashi T., Oswald E.

J. Bacteriol., 190: 275-285, 2008. 

Distribution of stable DnaA-binding sites on the Bacillus Subtilis genome detected using a modified ChIP-chip method.

Ishikawa S., Ogura Y., Yoshimura M, Okumura H, Cho E, Kawai Y, Kurokawa K, Oshima T, Ogasawara N.

DNA Res., 14:155-168, 2007. 

Comparative metagenomics revealed commonly enriched gene sets in human gut microbiomes.

Kurokawa K., Itoh T., Kuwahara T., Oshima K., Toh H., Toyoda A., Takami H., Morita H., Sharma VK., Srivastava TP., Taylor TD., Noguchi H., Mori H., Ogura Y., Ehrlich DS., Itoh K., Takagi T., Sakaki Y., Hayashi T., Hattori M.

DNA Res., 14: 169-181, 2007. 

Extensive genomic diversity and selective conservation of virulence-determinants in enterohemorrhagic Escherichia coli strains of O157 and non-O157 serotypes.

Ogura Y., Ooka T., Asadulghani., Terajima J., Nougayrède J-P., Kurokawa K., Tashiro K., Tobe T., Nakayama K., Kuhara S., Oswald E., Watanabe H., Hayashi T.

Genome Biol., 8: R138, 2007. 

An improved DNA isolation method for metagenomic analysis of the microbial flora of the human intestine.

Morita H., Kuwahara T., Okushima K., Sasamoto H., Itoh K., Hattori M., Hayashi T., Takami H.

Microbes Environ., 22: 214-222, 2007.

TccP2-mediated subversion of actin dynamics by EPEC 2 – a distinct evolutionary lineage of enteropathogenic Escherichia coli.

Whale A., Hernandes RT., Ooka T., Krause G., Schuller S., Garmendia J., Crowther L., Vieira MA., Ogura Y., Phillips AD., Beutin L., Gomes TA., Hayashi T., Frankel G.

Microbiology, 153: 1743-1755, 2007. 

Characterization of tccP2 carried by atypical enteropathogenic Escherichia coli.

Ooka T., Vieira MA., Ogura Y., Beutin L., Ragione R. L., van Diemen P. M., Stevens M. P., Aktan I., Cawthraw S., Best A., Hernandes R. T., Krause G., Gomes T. A. T., Hayashi T., Frankel G.

FEMS Microbiol. Lett., 271: 126-135, 2007. 

TccP2 of O157:H7 and non-O157 enterohemorrhagic Escherichia coli (EHEC): challenging the dogma of EHEC-induced actin polymerization.

Ogura Y., Ooka T., Whale A., Garmendia J., Beutin L., Tennant S., Krause G., Morabito S., Chinen I., Tobe T., Abe H., Tozzoli R., Caprioli A., Rivas M., Browne R. R., Hayashi T., Frankel G.

Infect. Immun., 75: 604-612, 2007. 

Microbiology. Breaking the barrier between commensalism and pathogenicity.

Hayashi T.

Science, 313: 772-773, 2006. 

An extensive repertoire of type III secretion effectors in Escherichia coli O157 and the role of lambdoid phages in their dissemination.

Tobe T., Beatson S. A., Taniguchi H., Abe H., Bailey C. M., Fivian A., Younis R., Matthews S., Marches O., Frankel G., Hayashi T., Pallen M. J.

Proc. Natl. Acad. Sci. USA, 103: 14941-14946, 2006. 

ppGpp with DksA controls gene expression in the locus of enterocyte effacement (LEE) pathogenicity island of enterohaemorrhagic Escherichia coli through activation of two virulence regulatory genes.

Nakanishi N., Abe H., Ogura Y., Hayashi T., Tashiro K., Kuhara S., Sugimoto N., Tobe T.

Mol. Microbiol., 61: 194-205, 2006. 

Complexity of the genomic diversity in enterohemorrhagic Escherichia coli O157 revealed by the combinational use of the O157 Sakai OligoDNA microarray and the Whole Genome PCR scanning.

Ogura Y., Kurokawa K., Ooka T., Tashiro K., Tobe T., Ohnishi M., Nakayama K., Morimoto T., Terajima J., Watanabe H., Kuhara S., Hayashi T.

DNA Res., 13: 3-14, 2006. 

Bacillus subtilis YabA is involved in determining the timing and synchrony of replication initiation.

Hayashi M., Ogura Y., Harry EJ., Ogasawara N.. and Moriya S.

FEMS Microbiol. Lett., 247:73-79, 2005. 

The genome sequence of Clostridium botulinum type C neurotoxin-converting phage and the molecular mechanisms of unstable lysogeny.

Sakaguchi Y., Hayashi T., Kurokawa K., Nakayama K., Oshima K., Fujinaga Y., Ohnishi M., Ohtsubo E., Hattori M., Oguma K.

Proc. Natl. Acad. Sci. USA, 102: 17472-17477, 2005. 

Dual regulatory pathways integrating the RcsC-RcsD-RcsB signalling system control enterohaemorrhagic Escherichia coli pathogenicity.

Tobe T., Ando H., Ishikawa H., Abe H., Tashiro K., Hayashi T., Kuhara S., Sugimoto N.

Mol. Microbiol., 58 : 320-333, 2005. 

2000年〜2004年

Genomic analysis of Bacteroides fragilis reveals extensive DNA inversions regulating cell surface adaptation.

Kuwahara T., Yamashita A., Hirakawa H., Nakayama H., Toh H., Okada N., Kuhara S., Hattori M., Hayashi T., Ohnishi Y.

Proc. Natl. Acad. Sci. USA, 101: 14919-14924, 2004. 

Increasing the ratio of Soj to Spo0J promotes replication initiation in Bacillus subtilis.

Ogura Y., Ogasawara N., Harry EJ., Moriya S.

J. Bacteriol., 185:6316-6324, 2003.

Two different mechanisms are involved in the extremely high-level benzalkonium chloride resistance of a Pseudomonas fluorescens strain.

Nagai K., Murata T., Ohta S., Zenda H., Ohnishi M., Hayashi T.

Microbiol. Immunol., 47: 709-715, 2003. 

Physical and genetic map of Enterococcus faecium ATCC19434 and demonstration of intra- and interspecific genomic diversity in enterococci.

Oana K., Okimura Y., Kawakami Y., Hayashida N., Shimosaka M., Okazaki M., Hayashi T., Ohnishi M.

FEMS Microbiol. Lett., 207: 133-139, 2002. 

Complete nucleotide sequence of plasmid Rts1: implications for evolution of large plasmid genomes.

Murata T., Ohnishi M., Ara T., Kaneko J., Han C-G., Li Y-F., Takashima K., Nojima H., Nakayama K., Kaji A., Kamio Y., Miki T., Mori H., Ohtsubo E., Terawaki Y., Hayashi T.

Mol. Microbiol., 31: 399-419, 1999.2002.

Clonal association of Staphylococcus aureus causing bullous impetigo and the emergence of new methicillin-resistant clonal groups in Kansai district in Japan.

Yamaguchi T., Yokota Y., Terajima J., Hayashi T., Aepfelbacher M., Ohara M., Komatsuzawa H., Watanabe H., Sugai M.

J.Infect. Dis., 185: 1511-1516, 2002. 

Genomic diversity of enterohemorrhagic Escherichia coli O157 revealed by whole genome PCR Scanning.

Ohnishi M., Terajima J., Kurokawa K., Nakayama K., Ogura Y., Tamura H., Watanabe H., Hayashi T.

Proc. Natl. Acad. Sci. USA, 99: 17043-17048, 2002. 

Autoregulation of the dnaA-dnaN operon and effects of DnaA protein levels on replication initiation in Bacillus subtilis.

Ogura Y., Imai Y., Ogasawara N. and Moriya S.

J. Bacteriol., 183:3833-41, 2001. 

Specific protein-DNA and protein-protein interaction in the hig gene system, a plasmid-borne proteic killer gene system of plasmid Rts1.

Tian Q. B., Ohnishi M., Murata T., Nakayama K., Terawaki Y., Hayashi T.

Plasmid, 45: 63-74, 2001. 

Molecular and epidemiological study of the first outbreak of vanB type vancomycin-resistant Enterococcus faecalis in Japan.

Oana K., Kawakami Y., Ohnishi M., Ishikawa M., Hirota M., Tozuka M., Atarashi K., Baba K., Fujiki K., Okazaki M., Honda T., Hayashi T.

Jpn. J. Infect. Dis., 54: 17-22, 2001. 

Diversification of Escherichia coli genomes: are bacteriophages the major contributors?

Ohnishi M., Kurokawa K., Hayashi T.

Trends Microbiol., 9: 481-485, 2001. 

toxB gene on pO157 of enterohemorrhagic Escherichia coli O157:H7 is required for full epithelial cell adherence phenotype.

Tatsuno I., Horie M., Abe H., Miki T., Makino K., Shinagawa H., Taguchi H., Kamiya S., Hayashi T., Sasakawa C.

Infect. Immun., 69: 6660-6669, 2001. 

Complete nucleotide sequence of a Staphylococcus aureus exfoliative toxin B plasmid and identification of a novel ADP-ribosyltransferase, EDIN-C.

Yamaguchi T., Hayashi T., Takami H., Ohnishi M., Murata T., Nakayama K., Asakawa K., Ohara M., Komatsuzawa H., Sugai M.

Infect. Immun., 69: 7760-7771, 2001. 

Association of the urease gene with enterohemorrhagic Escherichia coli strains irrespective of their serogroups.

Nakano M., Iida T., Ohnishi M., Kurokawa K., Takahashi A., Tsukamoto T., Yasunaga T., Hayashi T., Honda T.

J. Clin. Microbiol., 39: 4541-4543, 2001 

DNA inversion in the tail fiber gene alters the host range specificity of carotovoricin Er, a phage-tail-like bacteriocin of phytopathogenic Erwinia carotovora subsp. carotovora Er.

Nguyen H.A., Tomita T., Hirota M., Kaneko J., Hayashi T., Kamio Y.

J. Bacteriol., 183: 6274-6281, 2001. 

Complete genome sequence of enterohemorrhagic Escherichia coli O157:H7 and genomic comparison with a laboratory strain K-12.

Hayashi T., Makino K., Ohnishi M., Kurokawa K., Ishii K., Yokoyama K., Han C.-G., Ohtsubo E., Nakayama K., Murata T., Tanaka M., Tobe T., Iida T., Takami H., Honda T., Sasakawa C., Ogasawara N., Yasunaga T., Kuhara S., Shiba T., Hattori M., Shinagawa H.

DNA Res., 8: 11-22, 2001 (supplement 8: 47-52, 2001). 

Development of disinfectant mats and evaluation of their effectiveness.

Ohta S., Nagai K., Zenda H., Ogata H., Hayashi T., Oguchi M., Okimura Y., Akahan T., Saitou H., Kawakami Y.

Biocontrol Science, 5: 1-7, 2000.

Comparative analysis of the whole set of rRNA operons between an enterohemorrhagic Escherichia coli O157:H7 Sakai strain and an Escherichia coli K-12 strain MG1655.

Ohnishi M., Murata T., Nakayama K., Kuhara S., Hattori M., Kurokawa K., Yasunaga T., Yokoyama K., Makino K., Shinagawa H., Hayashi T.

Syst. Appl. Microbiol., 23: 315-324, 2000.　

The R-type pyocin of Pseudomonas aeruginosa is related to P2 phage, and the F-type is related to lambda phage.

Nakayama K., Takashima K., Ishihara H., Shinomiya T., Kageyama M., Kanaya S., Ohnishi M., Murata T., Mori H., Hayashi T.

Mol. Microbiol., 38: 213-231, 2000.　

Phage conversion of exfoliative toxin A production in Staphylococcus aureus.

Yamaguchi T., Hayashi T., Takami H., Nakasone K., Ohnishi M., Nakayama K., Yamada S., Komatsuzawa H., Sugai M.

Mol. Microbiol., 38: 694-705, 2000.　

Molecular analysis of the folC gene of Pseudomonas aeruginosa.

Murata T., Bognar A. L., Hayashi T., Ohnishi M., Nakayama K., Terawaki Y.

Microbiol. Immunol., 44: 879-886, 2000.　

Complete nucleotide sequence of the prophage VT1-Sakai carrying the Shiga toxin 1 genes of the enterohemorrhagic Escherichia coli O157:H7 strain derived from the Sakai outbreak.

Yokoyama K., Makino K., Kubota Y., Watanabe M., Kimura S., Yutsudo C. H., Kurokawa K., Ishii K., Hattori M., Tatsuno I., Abe H., Yoh M., Iida T., Ohnishi M., Hayashi T., Yasunaga T., Honda T., Sasakawa C., Shinagawa H.

Gene, 258: 127-139, 2000.　

1999年以前

Molecular cloning, sequencing, purification, and characterization of Pseudomonas aeruginosa ribosome recycling factor.

Ohnishi M., Jonosi L., Shuda M., Matsumoto H., Hayashi T., Terawaki Y., Kaji A.

J. Bacteriol., 181: 1281-1291, 1999.　

Complete DNA sequence and structural analysis of the enteropathogenic Escherichia coli adherence factor plasmid.

Tobe T., Hayashi T., Han C.G., Schoolnik G.K., Ohtsubo E., Sasakawa C.

Infect. Immun., 67: 5455-5462, 1999.　

Complete nucleotide sequence of the prophage VT2-Sakai carrying the verotoxin 2 genes of the enterohemorrhagic Escherichia coli O157:H7 derived from the Sakai outbreak.

Makino K., Yokoyama K., Kubota Y., Yutsudo C.H., Kimura S., Kurokawa K., Ishii K., Hattori M., Abe H., Iida T., Yamamoto K., Ohnishi M., Hayashi T., Yasunaga T., Honda T., Sasakawa C., Shinagawa H.

Genes Genet. Syst., 74: 227-239, 1999.　

Chromosome of the enterohemorrhagic Escherichia coli O157:H7; comparative analysis with K-12 MG1655 revealed the acquisition of a large amount of foreign DNAs.

Ohnishi M., Tanaka C., Kuhara S., Ishii K., Hattori M., Kurokawa K., Yasunaga T., Makino K., Shinagawa H., Murata T., Nakayama K., Terawaki Y., Hayashi T.

DNA Res., 6: 361-368, 1999.　

The complete nucleotide sequence of φCTX, a cytotoxin-converting phage of Pseudomonas aeruginosa: implications for phage evolution and horizontal gene transfer via bacteriophages.

Nakayama K., Kanaya S., Ohnishi M., Terawaki Y., Hayashi T.

Mol. Microbiol., 31: 399-419, 1999.　

Complete nucleotide sequences of 93-kb and 3.3-kb plasmids of an enterohemorrhagic Escherichia coli O157:H7 derived from Sakai outbreak.

Makino K., Ishii K., Yasunaga T., Hattori M., Yokoyama K., Yutsudo C.H., Kubota Y., Yamaichi Y., Iida T., Yamamoto K., Honda T., Han C., Ohtsubo E., Kasamatsu M., Hayashi T., Kuhara S., Shinagawa H.

DNA Res., 5: 1-9, 1998.　

Purification and characterization of procytotoxin of Pseudomonas aeruginosa. Dimer to monomer conversion of protoxin by proteolytic activation.

Ohnishi M., Hayashi T., Terawaki Y.

J. Biol. Chem., 273: 453-458, 1998.　

Functional domains of Rts1 and P1 RepA proteins for initiation of replication.

Li Y.F., Hayashi T., Terawaki Y.

Plasmid, 40: 140-149, 1998.　

Gene product identification and promoter analysis of hig locus of plasmid Rts1.

Tian Q.B., Hayashi T., Murata T., Terawaki Y.

Biochem. Biophys. Res. Commun., 225: 679-684, 1996.　

Multiple mitochondrial DNA deletions in a patient with mitochondrial myopathy and cardiomyopathy but no ophthalmoplegia.

Takei Y., Ikeda S., Yanagisawa N., Takahashi W., Sekiguchi M., Hayashi T.

Muscle Nerve., 18: 1321-1325, 1995.　

Analysis of functional domains of Rts1 RepA by means of a series of hybrid proteins with P1 RepA.

Tabuchi A., Ohnishi M., Hayashi T., Terawaki Y.

J. Bacteriol., 177: 4028-4035, 1995.　

IgA protease from Neisseria gonorrhoeae inhibits exocytosis in bovine chromaffin cells like tetanus toxin.

Binscheck T., Bartels F., Bergel H., Bigalke H., Yamasaki S., Hayashi T., Niemann H., Pohlner J.

J. Gen. Microbiol., 139: 2343-2351, 1993.　

Disassembly of the reconstituted synaptic vesicle membrane fusion complex in vitro.

Hayashi T., Yamasaki S., Nauenburg S., Binz T., Niemann H.

EMBO J., 14: 2317-2325, 1995.　

Botulinum neurotoxin type G proteolyses the Ala81-Ala82 bond of rat synaptobrevin 2.

Yamasaki S., Binz T., Hayashi T., Szabo E., Yamasaki N., Eklund M., Jahn R., Niemann H.

Biochem. Biophys. Res. Commun., 200: 829-835, 1994.　

Synaptic vesicle membrane fusion complex: action of clostridial neurotoxins on assembly.

Hayashi T., McMahon H., Yamasaki S., Binz T., Hata Y., Sudhof T.C., Niemann H.

EMBO J., 13: 5051-5061, 1994.　

Cytotoxin-converting phages, φCTX and PS21, are R pyocin-related phages.

Hayashi T., Matsumoto H., Ohnishi M., Yokota S., Shinoyama T., Kageyama M., Terawaki Y.

FEMS Microbiol. Let., 122: 239-244, 1994.　

Identification of the lipopolysaccharide core region as the receptor site for a cytotoxin-converting phage, φCTX, of Pseudomonas aeruginosa.

Yokota S., Hayashi T., Matsumoto H.

J. Bacteriol., 176: 5262-5269, 1994.　

Mechanism of the cytolytic action of Pseudomonas aeruginosa cytotoxin: oligomerization of the cytotoxin on target membranes.

Ohnishi M., Hayashi T., Tomita T., Terawaki Y.

FEBS. Let., 356: 357-360, 1994.　

Identification of two distinct NADH oxidases corresponding to H₂O₂-forming oxidase and H₂O-forming oxidase induced in Streptococcus mutans.

Higuchi M., Shimada M., Yamamoto Y., Hayashi T., Koga T., Kamio Y.

J. Gen. Microbiol., 139: 2343-2351, 1993.　

Molecular analysis of a cytotoxin-converting phage, φCTX, of Pseudomonas aeruginosa: structure of the attP–cos–ctx region and integration into the serine tRNA gene.

Hayashi T., Matsumoto H., Ohnishi M., Terawaki Y.

Mol. Microbiol., 7: 657-667, 1993.　

Function of the N-terminal half of RepA in activation of Rts1 ori.

Terawaki Y., Itoh Y., Zeng H., Hayashi T., Tabuchi A.

J. Bacteriol., 174: 6904-6910, 1992.　

Isolation and characterization of Shewanella alga from human clinical specimens and emendation of the description of S. alga Simidu et al., 1990, 335.

Nozue H., Hayashi T., Hashimoto Y., Ezaki T., Hamasaki K., Ohwada K., Terawaki Y.

Int. J. System. Bacteriol., 42: 628-634, 1992.　

Site-directed mutations in the repA C-terminal region of plasmid Rts1: pleiotropic effects on the replication and autorepressor functions.

Zeng H., Hayashi T., Terawaki Y.

J. Bacteriol., 172: 2535-2540, 1990.　

Effects of mutations in the repA gene of plasmid Rts1 on plasmid replication and autorepressor function.

Terawaki Y., Nozue H., Zeng H., Hayashi T., Kamio Y., Itoh Y.

J. Bacteriol.,172: 786-792, 1990.　

Phage-conversion of cytotoxin production in Pseudomonas aeruginosa.

Hayashi T., Baba T., Matsumoto H., Terawaki Y.

Mol. Microbiol.. 4: 1703-1709, 1990.　

Pseudomonas aeruginosa cytotoxin: the nucleotide sequence of the gene and the mechanism of activation of the protoxin.

Hayashi T., Kamio Y., Hishinuma F., Usami Y., Titani K., Terawaki Y.

Mol. Microbiol., 3: 861-868, 1989.　

Purification and characterization of cytotoxin from the crude extract of Pseudomonas aeruginosa.

Hayashi T., Kamio Y., Terawaki Y.

Microb. Pathogenesis, 6: 103-112, 1989.　

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