{"id":5,"date":"2025-02-05T14:18:16","date_gmt":"2025-02-05T05:18:16","guid":{"rendered":"http:\/\/labmed.local\/virology\/?page_id=2"},"modified":"2025-08-12T19:32:14","modified_gmt":"2025-08-12T10:32:14","slug":"greeting","status":"publish","type":"page","link":"https:\/\/www.lab.med.kyushu-u.ac.jp\/virology\/greeting\/","title":{"rendered":"\u6559\u6388\u6328\u62f6"},"content":{"rendered":"\n

\u6804\u990a\u306a\u3069\u306e\u6761\u4ef6\u3055\u3048\u6574\u3048\u3070\u5897\u3048\u308b\u3053\u3068\u304c\u3067\u304d\u308b\u7d30\u83cc\u3068\u7570\u306a\u308a\u3001\u30a6\u30a4\u30eb\u30b9\u306f\u7d30\u80de\u306e\u4e2d\u3067\u3057\u304b\u5897\u6b96\u3067\u304d\u306a\u3044\u75c5\u539f\u4f53\u3067\u3059\u3002\u30a6\u30a4\u30eb\u30b9\u30b2\u30ce\u30e0\u30b5\u30a4\u30ba\u306f\u4ed6\u306e\u75c5\u539f\u4f53\u3088\u308a\u5c0f\u3055\u304f\u3001\u81ea\u8eab\u3067\u6301\u3064\u30a6\u30a4\u30eb\u30b9\u30bf\u30f3\u30d1\u30af\u8cea\u3082\u5c11\u306a\u3044\u305f\u3081\u3001\u7d30\u80de\u5185\u3067\u81ea\u8eab\u3092\u5897\u5e45\u3059\u308b\u305f\u3081\u306b\u8907\u6570\u306e\u5bbf\u4e3b\u56e0\u5b50\u3092\u5229\u7528\u3057\u3066\u3044\u307e\u3059\u3002\u30d2\u30c8\u306b\u306f20000\u500b\u4ee5\u4e0a\u306e\u30bf\u30f3\u30d1\u30af\u8cea\u304c\u5b58\u5728\u3059\u308b\u4e00\u65b9\u3067\u3001\u30a6\u30a4\u30eb\u30b9\u306f2\u3064\u3057\u304b\u30a6\u30a4\u30eb\u30b9\u30bf\u30f3\u30d1\u30af\u8cea\u3092\u6301\u305f\u306a\u3044\u3082\u306e\u3082\u3042\u308a\u307e\u3059\u3002\u3053\u306e\u3088\u3046\u306a\u75c5\u539f\u4f53\u304c\u7d30\u80de\u306e\u4e2d\u3067\u52b9\u7387\u7684\u306b\u5897\u6b96\u3067\u304d\u308b\u3053\u3068\u306f\u4e0d\u601d\u8b70\u3067\u3059\u3057\u3001\u30a6\u30a4\u30eb\u30b9\u7814\u7a76\u306e\u9762\u767d\u3055\u306f\u3053\u3053\u306b\u3042\u308b\u3068\u79c1\u306f\u601d\u3063\u3066\u3044\u307e\u3059\u3002\u307e\u305f\u3001\u30a6\u30a4\u30eb\u30b9\u306f\u591a\u69d8\u3067\u3042\u308b\u3068\u3044\u3046\u70b9\u3082\u8208\u5473\u6df1\u3044\u70b9\u3067\u3059\u3002\u809d\u708e\u30a6\u30a4\u30eb\u30b9\u3084\u30d2\u30c8\u514d\u75ab\u4e0d\u5168\u30a6\u30a4\u30eb\u30b9\uff08HIV\uff09\u306e\u3088\u3046\u306b\u6162\u6027\u611f\u67d3\u3059\u308b\u3053\u3068\u306b\u3088\u3063\u3066\u3001\u3086\u3063\u304f\u308a\u3068\u75c5\u539f\u6027\u3092\u793a\u3059\u3082\u306e\u3082\u3042\u308c\u3070\u3001\u30a4\u30f3\u30d5\u30eb\u30a8\u30f3\u30b6\u30a6\u30a4\u30eb\u30b9\u3084SARS-CoV\u306e\u3088\u3046\u306b\u6025\u901f\u306b\u611f\u67d3\u7d30\u80de\u3092\u7834\u58ca\u3057\u3001\u5f37\u304f\u514d\u75ab\u5fdc\u7b54\u3092\u8a98\u5c0e\u3059\u308b\u30a6\u30a4\u30eb\u30b9\u3082\u3042\u308a\u307e\u3059\u3002\u3053\u306e\u3088\u3046\u306b\u30a6\u30a4\u30eb\u30b9\u306f\u4e00\u3064\u4e00\u3064\u3001\u3069\u306e\u3088\u3046\u306b\u7d30\u80de\u306e\u4e2d\u3067\u5897\u6b96\u3059\u308b\u306e\u304b\u3068\u3044\u3046\u70b9\u3067\u5927\u304d\u304f\u591a\u69d8\u3067\u3059\u3002\u3057\u304b\u3082\u3001\u5897\u6b96\u306e\u904e\u7a0b\u3067\u3069\u3093\u3069\u3093\u5909\u7570\u3092\u84c4\u7a4d\u3057\u3001\u6027\u72b6\u3092\u5909\u3048\u3066\u3044\u304d\u3001\u7a2e\u6307\u5411\u6027\u3084\u81d3\u5668\u6307\u5411\u6027\u3092\u5909\u3048\u3066\u3044\u304d\u307e\u3059\u3002\u4eca\u56de\u306e\u65b0\u578b\u30b3\u30ed\u30ca\u30a6\u30a4\u30eb\u30b9\u3082\u4e16\u754c\u7684\u306a\u611f\u67d3\u62e1\u5927\u306e\u4e2d\u3067\u3001\u69d8\u3005\u306a\u5909\u7570\u3092\u84c4\u7a4d\u3057\u3001\u5897\u6b96\u6027\u3084\u75c5\u539f\u6027\u304c\u5909\u5316\u3057\u3066\u3044\u308b\u53ef\u80fd\u6027\u3082\u793a\u5506\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u79c1\u305f\u3061\u30a6\u30a4\u30eb\u30b9\u7814\u7a76\u8005\u306f\u65b0\u8208\u30a6\u30a4\u30eb\u30b9\u306e\u51fa\u73fe\u306b\u3044\u3061\u65e9\u304f\u5bfe\u5fdc\u3057\u3001\u523b\u4e00\u523b\u3068\u5909\u5316\u3059\u308b\u30a6\u30a4\u30eb\u30b9\u306b\u5408\u308f\u305b\u3066\u3053\u3061\u3089\u3082\u9069\u5fdc\u3057\u3001\u611f\u67d3\u5236\u5fa1\u306b\u8ca2\u732e\u3057\u3046\u308b\u7814\u7a76\u3092\u63a8\u9032\u3059\u308b\u3053\u3068\u304c\u4f7f\u547d\u3060\u3068\u8003\u3048\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n

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2025\u5e743\u6708 \u798f\u539f\u5d07\u4ecb<\/p>\n\n\n\n

<\/div>\n\n\n\n

\u7565\u6b74<\/h2>\n\n\n\n
\n
1998\u5e743\u6708<\/td>\u798f\u5ca1\u770c\u79c1\u7acb\u660e\u6cbb\u5b66\u5712\u9ad8\u7b49\u5b66\u6821\u3000\u5352\u696d<\/td><\/tr>
2004\u5e743\u6708<\/td>\u4e5d\u5dde\u5927\u5b66\u533b\u5b66\u90e8\u533b\u5b66\u79d1 \u5352\u696d<\/td><\/tr>
2004\u5e744\u6708<\/td>\u4e5d\u5dde\u5927\u5b66\u75c5\u9662\u3000\u81e8\u5e8a\u7814\u4fee\u533b<\/td><\/tr>
2005\u5e745\u6708<\/td>\u4f50\u8cc0\u770c\u7acb\u75c5\u9662\u597d\u751f\u9928\u3000\u81e8\u5e8a\u7814\u4fee\u533b<\/td><\/tr>
2010\u5e743\u6708<\/td>\u4e5d\u5dde\u5927\u5b66\u5927\u5b66\u9662\u533b\u5b66\u7814\u7a76\u79d1\u3000\u4fee\u4e86<\/td><\/tr>
2010\u5e744\u6708<\/td>\u5927\u962a\u5927\u5b66\u5fae\u751f\u7269\u75c5\u7814\u7a76\u6240\u5206\u5b50\u30a6\u30a4\u30eb\u30b9\u5206\u91ce\u3000\u7279\u4efb\u7814\u7a76\u54e1<\/td><\/tr>
2010\u5e744\u6708<\/td>\u65e5\u672c\u5b66\u8853\u632f\u8208\u4f1a\u7279\u5225\u7814\u7a76\u54e1\u3000PD<\/td><\/tr>
2011\u5e747\u6708<\/td>\u5927\u962a\u5927\u5b66\u5fae\u751f\u7269\u75c5\u7814\u7a76\u6240\u5206\u5b50\u30a6\u30a4\u30eb\u30b9\u5206\u91ce\u3000\u52a9\u6559<\/td><\/tr>
2017\u5e7412\u6708<\/td>\u5927\u962a\u5927\u5b66\u5fae\u751f\u7269\u75c5\u7814\u7a76\u6240\u5206\u5b50\u30a6\u30a4\u30eb\u30b9\u5206\u91ce\u3000\u51c6\u6559\u6388<\/td><\/tr>
2020\u5e745\u6708<\/td>\u5317\u6d77\u9053\u5927\u5b66\u5927\u5b66\u9662\u533b\u5b66\u7814\u7a76\u9662\u3000\u5fae\u751f\u7269\u90e8\u9580\u514d\u75ab\u5b66\u5206\u91ce\u3000\u6559\u6388<\/td><\/tr>
2024\u5e749\u6708<\/td>\u4e5d\u5dde\u5927\u5b66\u5927\u5b66\u9662\u533b\u5b66\u7814\u7a76\u9662\u3000\u30a6\u30a4\u30eb\u30b9\u5b66\u5206\u91ce\u3000\u6559\u6388
\u5317\u6d77\u9053\u5927\u5b66\u5927\u5b66\u9662\u533b\u5b66\u7814\u7a76\u9662\u3000\u5fae\u751f\u7269\u90e8\u9580\u514d\u75ab\u5b66\u5206\u91ce\u3000\u62db\u3078\u3044\u6559\u6388<\/td><\/tr><\/tbody><\/table><\/figure>\n<\/div>\n\n\n\n
<\/div>\n\n\n\n

\u4e3b\u306a\u696d\u7e3e<\/h2>\n\n\n\n
\n
    \n
  • Torii S, Ono C, Suzuki R, Morioka Y, Anzai I, Fauzyah Y, Maeda Y, Kamitani W, Fukuhara T<\/strong> (Corresponding author) and Matsuura Y. A novel reverse genetics system for SARS-CoV-2 by using circular polymerase extension reaction. Cell Rep<\/strong>. 2021 Apr 20;35(3):109014.<\/li>\n\n\n\n
  • Ono C,\u00a0Fukuhara T<\/strong>\u00a0(Corresponding author), Li S, Wang J, Sato A, Izumi T, Fauzyah Y, Yamamoto T, Morioka Y, Dokholyan NV, Standley DM and Matsuura Y. Various miRNAs compensate the role of miR-122 on HCV replication.\u00a0PLoS Pathog.<\/strong>\u00a016(6): e1008308, 2020<\/li>\n\n\n\n
  • Tamura T, Igarashi M, Enkhbold B, Suzuki T, Okamatsu M, Ono C, Mori H, Izumi T, Sato A, Fauzyah Y, Okamoto T, Sakoda Y, Fukuhara T<\/strong> (Corresponding author) and Matsuura Y. In vivo dynamics of reporter Flaviviridae viruses. J Virol<\/strong>. 93(22): e01191-19, 2019<\/li>\n\n\n\n
  • Mori H, Fukuhara T<\/strong> (Corresponding author), Ono C, Tamura T, Sato A, Fauzyah Y, Wada M, Okamoto T, Noda T, Yoshimori T and Matsuura Y. (2018) Induction of selective autophagy in cells replicating hepatitis C virus genome. J Gen Virol.<\/strong> 99(12): 1643-57, 2018<\/li>\n\n\n\n
  • Tamura T, Fukuhara T<\/strong> (Corresponding author), Uchida T, Ono C, Mori H, Sato A, Fauzyah Y, Okamoto T, Kurosu T, Setoh YX, Imamura M, Tautz N, Sakoda Y, Khromykh AA, Chayama K and Matsuura Y. Characterization of recombinant Flaviviridae viruses possessing a small reporter tag. J Virol<\/strong>. 92(2): e01582-17, 2018<\/li>\n\n\n\n
  • Kurihara T, Fukuhara T<\/strong> (Corresponding author), Ono C, Yamamoto S, Uemura K, Okamoto T, Sugiyama M, Motooka D, Nakamura S, Ikawa M, Mizokami M, Maehara Y and Matsuura Y. Suppression of HBV replication by the expression of nickase- and nuclease dead-Cas9. Sci Rep.<\/strong> 7(1): 6122, 2017<\/li>\n\n\n\n
  • Fukuhara T<\/strong>, Tamura T, Ono C, Shiokawa M, Mori H, Uemura K, Yamamoto S, Kurihara T, Okamoto T, Suzuki R, Yoshii K, Kurosu T, Igarashi M, Aoki H, Sakoda Y and Matsuura Y. Host-derived apolipoproteins play comparable roles with viral secretory proteins Erns and NS1 in the infectious particle formation of Flaviviridae. PLoS Pathog<\/strong>. 13(6): e1006475, 2017<\/li>\n\n\n\n
  • Ono C, Fukuhara T<\/strong> (Equally first author), Motooka D, Nakamura S, Okuzaki D, Yamamoto S, Tamura T, Mori H, Sato A, Uemura K, Fauzyah Y, Kurihara T, Suda T, Nishio A, Hmwe SS, Okamoto T, Tatsumi T, Takehara T, Chayama K, Wakita T, Koike K and Matsuura Y. Characterization of miR-122-independent propagation of HCV. PLoS Pathog.<\/strong> 13(5): e1006374, 2017<\/li>\n\n\n\n
  • Yamamoto S, Fukuhara T<\/strong> (Equally first author), Ono C, Uemura K, Kawachi Y, Shiokawa M, Mori H, Wada M, Shima R, Okamoto T, Hiraga N, Suzuki R, Chayama K, Wakita T and Matsuura Y. Lipoprotein Receptors Redundantly Participate in Entry of Hepatitis C Virus. PLoS Pathog.<\/strong> 12(5): e1005610, 2016<\/li>\n\n\n\n
  • Fukuhara T<\/strong>, Ono C, Puig-Basagoiti F and Matsuura Y. Roles of Lipoproteins and Apolipoproteins in Particle Formation of Hepatitis C Virus. Trends Microbiol.<\/strong> 23(10): 618-29, 2015<\/li>\n\n\n\n
  • Fukuhara T<\/strong>, Wada M, Nakamura S, Ono C, Shiokawa M, Yamamoto S, Motomura T, Okamoto T, Okuzaki D, Yamamoto M, Saito I, Wakita T, Koike K and Matsuura Y. Amphipathic a-helices in apolipoproteins are crucial to the formation of infectious hepatitis C virus particles. PLoS Pathog.<\/strong> 10(12): e1004534, 2014<\/li>\n\n\n\n
  • Fukuhara T<\/strong>, Kambara H, Shiokawa M, Ono C, Katoh H, Morita E, Okuzaki D, Maehara Y, Koike K and Matsuura Y. Expression of microRNA miR-122 facilitates an efficient replication in nonhepatic cells upon infection with hepatitis C virus. J Virol<\/strong>. 86(15): 7918-33, 2012<\/li>\n\n\n\n
  • Fukuhara T<\/strong>, Taketomi A, Motomura T, Okano S, Ninomiya A, Abe T, Uchiyama H, Soejima Y, Shirabe K, Matsuura Y and Maehara Y. Variants in IL28B in liver recipients and donors correlate with response to peg-interferon and ribavirin therapy for recurrent hepatitis C. Gastroenterology<\/strong>. 139(5): 1577-85, 2010<\/li>\n\n\n\n
  • Fukuhara T <\/strong>(Corresponding author), Taketomi A, Okano S, Ikegami T, Soejima Y, Shirabe K and Maehara Y. Mutations in hepatitis C virus genotype 1b and the sensitivity of interferon-ribavirin therapy after liver transplantation. J Hepatol<\/strong>. 52(5): 672-80, 2010<\/li>\n<\/ul>\n<\/div>\n","protected":false},"excerpt":{"rendered":"

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