{"id":346,"date":"2017-10-04T19:08:02","date_gmt":"2017-10-04T10:08:02","guid":{"rendered":"https:\/\/www.lab.med.kyushu-u.ac.jp\/scr\/?page_id=346"},"modified":"2025-05-16T17:04:56","modified_gmt":"2025-05-16T08:04:56","slug":"%e7%a0%94%e7%a9%b6%e5%86%85%e5%ae%b9%ef%bc%9a%e3%81%8c%e3%82%93%e5%b9%b9%e7%b4%b0%e8%83%9e%e5%8c%bb%e5%ad%a6%e5%88%86%e9%87%8e%ef%bc%88%e3%81%8c%e3%82%93%e6%b2%bb%e7%99%82%ef%bc%89","status":"publish","type":"page","link":"https:\/\/www.lab.med.kyushu-u.ac.jp\/scr\/research\/%e7%a0%94%e7%a9%b6%e5%86%85%e5%ae%b9\/%e7%a0%94%e7%a9%b6%e5%86%85%e5%ae%b9%ef%bc%9a%e3%81%8c%e3%82%93%e5%b9%b9%e7%b4%b0%e8%83%9e%e5%8c%bb%e5%ad%a6%e5%88%86%e9%87%8e%ef%bc%88%e3%81%8c%e3%82%93%e6%b2%bb%e7%99%82%ef%bc%89\/","title":{"rendered":"\u7814\u7a76\u5185\u5bb9\uff1a\u304c\u3093\u5e79\u7d30\u80de\u533b\u5b66\u5206\u91ce\uff08\u304c\u3093\u6cbb\u7642\uff09"},"content":{"rendered":"

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\n\u73fe\u5728\u3001\u304c\u3093\u5e79\u7d30\u80de\u306b\u304a\u3044\u3066\u4ee3\u8b1d\u3084\u5206\u5b50\u30b7\u30b0\u30ca\u30eb\u3092\u5236\u5fa1\u3059\u308b\u3053\u3068\u3067\u3001\u304c\u3093\u306e\u5897\u6b96\u3084\u767a\u75c7\u306b\u5bfe\u3059\u308b\u5f71\u97ff\u3092\u660e\u3089\u304b\u306b\u3057\u305f\u3044\u3068\u8003\u3048\u3066\u3044\u307e\u3059\u3002<\/p>\n

\u304c\u3093\u5e79\u7d30\u80de\u30cb\u30c3\u30c1\u306e\u540c\u5b9a\u3068\u5236\u5fa1<\/h2>\n

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\n\u672c\u7814\u7a76\u3067\u306f\u3001\u304c\u3093\u5e79\u7d30\u80de\u3092\u652f\u6301\u3059\u308b\u30cb\u30c3\u30c1\u7d30\u80de\u3092\u7279\u5b9a\u3059\u308b\u305f\u3081\u3001\u907a\u4f1d\u5b50\u6b20\u640d\u30de\u30a6\u30b9\u3084\u9020\u8840\u5668\u816b\u760d\u30e2\u30c7\u30eb\u30de\u30a6\u30b9\u3092\u7528\u3044\u3001\u30db\u30fc\u30eb\u30de\u30a6\u30f3\u30c83D\u30a4\u30e1\u30fc\u30b8\u30f3\u30b0\u3084\u3001\u86cd\u5149\u751f\u4f53\u30a4\u30e1\u30fc\u30b8\u30f3\u30b0\u306a\u3069\u3092\u884c\u3044\u3001\u6a19\u7684\u3068\u306a\u308b\u7d30\u80de\u306e\u6a5f\u80fd\u3092\u89e3\u6790\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n

\"\"<\/p>\n

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\"\"
\n\u56f31. \u9aa8\u5185\u819c\u30cb\u30c3\u30c1\u306f\u767d\u8840\u75c5\u5e79\u7d30\u80de\u306e\u9759\u6b62\u72b6\u614b\u3092\u7dad\u6301\u3059\u308b<\/strong>
\n\u6211\u3005\u306f\u3001LSC\u304c\u6f5c\u3080\u767d\u8840\u75c5\u30cb\u30c3\u30c1\u306b\u3064\u3044\u3066\u7740\u76ee\u3057\u3066\u767d\u8840\u75c5\u30de\u30a6\u30b9\u30e2\u30c7\u30eb\u306e\u89e3\u6790\u3092\u884c\u3044\u3001\u9aa8\u5185\u819c\u30cb\u30c3\u30c1\u306b\u5b58\u5728\u3059\u308b Alcam \u967d\u6027\u306ebone lining cell (Alcam+ BLC) \u304c\u3001LSC\u3092\u6cbb\u7642\u62b5\u6297\u6027\u306e\u300c\u9759\u6b62\u72b6\u614b\u300d\u306b\u7dad\u6301\u3059\u308b\u91cd\u8981\u306a\u5f79\u5272\u3092\u679c\u305f\u3057\u3066\u3044\u308b\u3053\u3068\u3092\u660e\u3089\u304b\u306b\u3057\u307e\u3057\u305f\u3002\u7d30\u80de\u5468\u671f\u304c\u9759\u6b62\u671f\u306b\u3042\u308bLSC\u306f\u3001Alcam+ BLC \u304c\u8c4a\u5bcc\u306a\u9818\u57df\u306b\u96c6\u7a4d\u3057\u3066\u3044\u307e\u3057\u305f\u3002\u3055\u3089\u306b\u3001LSC\u304b\u3089\u5206\u6ccc\u3055\u308c\u308b TGF-\u03b21 \u304c Alcam+ BLC \u306e\u30aa\u30b9\u30c6\u30aa\u30dd\u30f3\u30c1\u30f3 (OPN) \u7523\u751f\u3092\u4fc3\u9032\u3057\u3001\u5206\u6ccc\u3055\u308c\u305f\u30aa\u30b9\u30c6\u30aa\u30dd\u30f3\u30c1\u30f3\u304cLSC\u3092\u9aa8\u5185\u819c\u30cb\u30c3\u30c1\u306b\u7559\u3081\u3001\u9759\u6b62\u72b6\u614b\u3092\u7dad\u6301\u3059\u308b\u3068\u3044\u3046 TGF-\u03b21\/Tgfbr2\/OPN \u30b7\u30b0\u30ca\u30eb\u7d4c\u8def\u3092\u540c\u5b9a\u3057\u307e\u3057\u305f\u3002\u3053\u308c\u3089\u306e\u77e5\u898b\u306f\u3001\u5f93\u6765\u306e\u5316\u5b66\u7642\u6cd5\u3067\u306f\u6392\u9664\u304c\u56f0\u96e3\u3067\u3042\u3063\u305f\u9759\u6b62\u671fLSC\u3092\u6a19\u7684\u3068\u3057\u305f\u6cbb\u7642\u85ac\u958b\u767a\u304c\u53ef\u80fd\u306b\u306a\u308b\u3068\u671f\u5f85\u3055\u308c\u307e\u3059\u3002
\n\uff08Ngan Thi Kim Nguyen et al., Leukemia, 2025<\/a>\uff09<\/p>\n","protected":false},"excerpt":{"rendered":"

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